Evidence map›Paper›PMID 28584678›Full record

ArticleSurgical neurology international2017

Preventive effect of tamsulosin on postoperative urinary retention in neurosurgical patients.

Azam Basheer, Mohammed Alsaidi, Lonni Schultz, Mokbel Chedid, Muwaffak Abdulhak, Donald Seyfried

3 registry-linked trialsOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Surgical neurology international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 8 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 3 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03314025 phase2unknown statusnot on this map

Prophylactic Tamsulosin in Prevention of Post-operative Urinary Retention in Men After Transanal Endoscopic Microsurgery: A Multicenter Randomized, Double-blind, Placebo-controlled Clinical Trial

TypeinterventionalSponsorCHU de Quebec-Universite LavalRan2017 to 2022Enrolled158ConditionsUrinary RetentionArmsTamsulosin Hydrochloride 0.4 MG, Placebo oral capsule, Foley catheter
NCT03976934 phase1 / phase2completednot on this mapstarted 2020, after this paper: background citation

Prophylactic Administration of Alpha Blockers for Prevention of Post Operative Urinary Retention in Males Undergoing Open Inguinal Hernia Repair Under Spinal Anaesthesia.

TypeinterventionalSponsorGeorgios KoukoulisRan2020 to 2021Enrolled100ConditionsInguinal Hernia, Urinary RetentionArmsTamsulosin, Placebo oral tablet
NCT04159077 phase3unknown statusnot on this mapstarted 2021, after this paper: background citation

Reduction of Post-Operative Urinary Retention With Tamsulosin Versus Placebo (REPOURT- P) Trial

TypeinterventionalSponsorMcMaster UniversityRan2021 to 2023Enrolled350ConditionsUrinary Catheterization, Thoracic Surgery, Thoracic Epidural AnalgesiaArmsTamsulosin Hydrochloride, Placebos
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 3 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Review
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Azam BasheerDepartment of Neurosurgery, Henry Ford Hospital, Detroit, Michigan, USA.
Mohammed AlsaidiDepartment of Neurosurgery, Henry Ford Hospital, Detroit, Michigan, USA.
Lonni SchultzDepartment of Public Health Sciences, Henry Ford Hospital, Detroit, Michigan, USA.
Mokbel ChedidDepartment of Neurosurgery, Henry Ford Hospital, Detroit, Michigan, USA.
Muwaffak AbdulhakDepartment of Neurosurgery, Henry Ford Hospital, Detroit, Michigan, USA.
Donald SeyfriedDepartment of Neurosurgery, Henry Ford Hospital, Detroit, Michigan, USA.
Henry Ford Hospital · USWinthrop-University Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPostoperative urinary retention (POUR) is common in neurosurgical patients. The use of alpha-blockade therapy, such as tamsulosin, has benefited many patients with a history of obstructive uropathy by decreasing lower urinary tract symptoms such as distension, infections, and stricture formation, as well as the incidence of POUR. For this study, we targeted patients who had undergone spinal surgery to examine the prophylactic effects of tamsulosin. Increased understanding of this therapy will assist in minimizing the morbidity of spinal surgery.

methodsWe enrolled 95 male patients undergoing spine surgery in a double-blind, randomized, placebo-controlled trial. Patients were randomly assigned to receive either preoperative tamsulosin (N = 49) or a placebo (N = 46) and then followed-up prospectively for the development of POUR after removal of an indwelling urinary catheter (IUC). They were also followed-up for the incidence of IUC reinsertions.

resultsThe rate of developing POUR was similar in both the groups. Of the 49 patients given tamsulosin, 16 (36%) developed POUR compared to 13 (28%) from the control group (

conclusionOverall, there was no statistically significant difference in the rates of developing POUR among patients in either group. POUR is caused by a variety of factors, and further studies are needed to shed light on its etiology.

Indexed as

Adrenergic alpha-antagonistsindwelling urinary catheterneurosurgerypostoperative urinary retentiontamsulosinurinary retention

Identifiers

PMID28584678
PMCPMC5445651
OpenAlexW2737377506

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.