Evidence map›Paper›PMID 28584636›Full record

ArticleBiomedical reports2017

ATP serves an anti-inflammatory role by enhancing β-defensin-2 response in acute pneumonia of rat.

Zhenwei Shen, Yun Zhou, Le Qu, Han Lei

Open access · hybridAbstract read
In one paragraph

Article in Biomedical reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Zhenwei ShenIntensive Care Unit, Shanghai International Medical Center, Shanghai 201318, P.R. China.
Yun ZhouDepartment of Cardiology, Chinese Traditional Medical Hospital Affiliated to Xinjiang Medical University, Urumqi, Xinjiang 830000, P.R. China.
Le QuDepartment of Cadre, Chinese Traditional Medical Hospital Affiliated to Xinjiang Medical University, Urumqi, Xinjiang 830000, P.R. China.
Han LeiDepartment of Respiratory Medicine, Shanghai East Hospital, Shanghai 200120, P.R. China.
Xinjiang Medical University · CNShanghai East Hospital · CNShanghai International Medical Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the current study was to evaluate the effect of ATP on the expression of rat β-defensin-2 (rBD-2) in a time-dependent manner, as well as its therapeutic value in an acute pneumonia rat model. A total of 30 rats as a treatment group and 30 as a control group were treated with the same dose of ATP and normal saline, respectively, lung tissues were isolated from rat and expression of rBD-2 mRNA was assessed with reverse transcription-quantitative polymerase chain reaction (RT-qPCR) at 12, 24 and 36 h following treatment. Rats were divided into five groups: The control group treated with normal saline, the

Indexed as

acute pneumoniaATPcephalosporinsβ-defensin-2

Identifiers

PMID28584636
PMCPMC5449963
OpenAlexW2613940832

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.