Evidence map›Paper›PMID 28584629›Full record

ArticleBiomedical reports2017

Role of the microRNA-29 family in fibrotic skin diseases.

Duygu Harmanci, Erdogan Pekcan Erkan, Ayse Kocak, Gul Guner Akdogan

Open access · bronzeAbstract read
In one paragraph

Article in Biomedical reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 43 citations in OpenAlex.

  1. The Wound-Heart Axis: Can Chronic Wounds Contribute to Cardiac Dysfunction?International journal of molecular sciences · 2026
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  14. The Potential Use of Cannabis in Tissue Fibrosis.Frontiers in cell and developmental biology · 2021
    Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. The Role of microRNAs in Organismal and Skin Aging.International journal of molecular sciences · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Duygu HarmanciDepartment of Molecular Medicine, Graduate School of Health Sciences, Dokuz Eylul University, Izmir 35340, Turkey.
Erdogan Pekcan ErkanDepartment of Medical Genetics, Medicum, University of Helsinki, 00014 Helsinki, Finland.
Ayse KocakDepartment of Molecular Medicine, Graduate School of Health Sciences, Dokuz Eylul University, Izmir 35340, Turkey.
Gul Guner AkdoganDepartment of Medical Biochemistry, School of Medicine, Izmir University of Economics, Balcova 35330, Izmir, Turkey.
Dokuz Eylül University · TRİzmir University of Economics · TRUniversity of Helsinki · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fibrotic skin diseases are characterized by the accumulation of collagen. The hallmarks of fibrotic skin diseases are unbalanced fibroblast proliferation and differentiation, extracellular matrix production and transforming growth factor-β signalling. Numerous studies have investigated the possibility that microRNAs (miRNAs or miRs) are involved in the pathogenesis of certain fibrotic diseases, including skin, heart, lung and liver diseases. miRNAs are a class of small non-coding RNAs, which modify gene expression by binding to target messenger RNA (mRNA) and blocking the translation or inducing the degradation of target mRNA. The biological relevance of miRNAs has been investigated in physiological and pathological conditions, and there is increasing evidence that the miR-29 family is associated with fibrotic diseases. The aim of the present review is to provide an up-to-date summary of current knowledge on the latest developments associated with the miR-29 family and fibrotic skin diseases.

Indexed as

fibrotic skin diseasesfunctionmicroRNA-29 familypathogenesisskin

Identifiers

PMID28584629
PMCPMC5449962
OpenAlexW2610765311

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.