ArticleJournal of clinical biochemistry and nutrition2017
Chemopreventive effects of a low-side-effect antibiotic drug, erythromycin, on mouse intestinal tumors.
Article in Journal of clinical biochemistry and nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 28 citations in OpenAlex.
- The gut microbiome in colorectal cancer: mechanisms of carcinogenesis and emerging microbiota-targeted therapies.Discover oncology · 2026Review
- New Marine Actinobacteria Strain,Microorganisms · 2025Article
- Antioxidant Role of Probiotics in Inflammation-Induced Colorectal Cancer.International journal of molecular sciences · 2024Review
- Theoretical basis validation and oxidative stress markers for cancer prevention clinical trials of aspirin.Scientific reports · 2023Article
- Erythromycin: an alternative for the management of oral mucositis?Medicina oral, patologia oral y cirugia bucal · 2022Review
- The Combination of Cigarette Smoking and Alcohol Consumption Synergistically Increases Reactive Carbonyl Species in Human Male Plasma.International journal of molecular sciences · 2021Article
- Article
- Microbiota, Bacterial Carbonic Anhydrases, and Modulators of Their Activity: Links to Human Diseases?Mediators of inflammation · 2021Review
- Gut Microbiota Manipulation as a Tool for Colorectal Cancer Management: Recent Advances in Its Use for Therapeutic Purposes.International journal of molecular sciences · 2020Review
- Clarithromycin inhibits autophagy in colorectal cancer by regulating the hERG1 potassium channel interaction with PI3K.Cell death & disease · 2020Article
- The Radical Scavenger NZ-419 Suppresses Intestinal Polyp Development inJournal of clinical medicine · 2020Article
- Sesame Lignans Suppress Age-Related Cognitive Decline in Senescence-Accelerated Mice.Nutrients · 2019Article
- Article
- AugmentedJournal of clinical biochemistry and nutrition · 2018Article
- Antibiotic-mediated bacteriome depletion in ApcCancer medicine · 2018Article
- Intestinal microbiota: a novel perspective in colorectal cancer biotherapeutics.OncoTargets and therapy · 2018Review
- Article
- Impact of Acetazolamide, a Carbonic Anhydrase Inhibitor, on the Development of Intestinal Polyps in Min Mice.International journal of molecular sciences · 2017Article
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is important to establish effective methods for preventing colorectal cancer because the number of colorectal cancer deaths is increasing. Erythromycin one of the macrolide antibiotics, has been shown to exert pleiotropic effects, such as anti-inflammatory and anti-oxidative effects, on mammalian cells. In the present study, we aimed to evaluate the preventive effects of erythromycin on intestinal carcinogenesis. We first confirmed that erythromycin suppresses the transcriptional activity of nuclear factor-κB and activator protein-1 and the expression of its downstream targets, interleukin-6 and cyclooxygenase-2 in human colon cancer cells. Next, we fed 5-week-old male
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.