Evidence map›Paper›PMID 28584287›Full record

ArticleMolecular psychiatry2017

Rescue of impaired sociability and anxiety-like behavior in adult cacna1c-deficient mice by pharmacologically targeting eIF2α.

Z D Kabir, A Che, D K Fischer, R C Rice, B K Rizzo, M Byrne, M J Glass, N V De Marco Garcia, A M Rajadhyaksha

Open access · greenAbstract read
In one paragraph

Article in Molecular psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 90 citations in OpenAlex.

  1. Progenitor Resilience and the Early Onset of Chronic Lung Diseases: NHLBI workshop report.American journal of respiratory cell and molecular biology · 2026
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  5. Astrocytic abnormalities in brain-specificChannels (Austin, Tex.) · 2025
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  8. Deletion ofbioRxiv : the preprint server for biology · 2025
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  9. The Impact of Overexpression of the Mouse Ortholog ofBiological psychiatry global open science · 2025
    Article
  10. Reduced Gene Dosage of the Psychiatric Risk GeneInternational journal of molecular sciences · 2025
    Article
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  16. Review
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  19. Review
  20. Alveolar epithelial regeneration in the aging lung.The Journal of clinical investigation · 2023
    Review

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Z D KabirPediatric Neurology, Pediatrics, Weill Cornell Medicine, New York, NY, USA.
A CheFeil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY, USA.
D K FischerPediatric Neurology, Pediatrics, Weill Cornell Medicine, New York, NY, USA.
R C RicePediatric Neurology, Pediatrics, Weill Cornell Medicine, New York, NY, USA.
B K RizzoPediatric Neurology, Pediatrics, Weill Cornell Medicine, New York, NY, USA.
M ByrnePediatric Neurology, Pediatrics, Weill Cornell Medicine, New York, NY, USA.
M J GlassFeil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY, USA.
N V De Marco GarciaFeil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY, USA.
A M RajadhyakshaPediatric Neurology, Pediatrics, Weill Cornell Medicine, New York, NY, USA.
Weill Cornell Medicine · USCornell University · USMIND Research Institute · US

Funding

Neural Mechanism for the assembly of GABAergic in the cerebral cortexR01MH110553 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI Natalia Vanesa De Marco Garcia · 2016 to 2026
$4.2M
The Role of Cav1.2 L-type Ca2+ Channels in Cocaine-Induced ReinstatementR01DA029122 · NIDA · WEILL MEDICAL COLL OF CORNELL UNIV · PI RAJADHYAKSHA, ANJALI M · 2012 to 2016
$2.1M
Mechanisms Underlying Activity-Dependent Interneuron DevelopmentR00MH095825 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI DE MARCO GARCIA, NATALIA VANESA · 2014 to 2016
$740k
NIDA NIH HHS R01 DA029122NIMH NIH HHS R00 MH095825NIMH NIH HHS R01 MH110553
6 · The paper itself

Abstract

CACNA1C, encoding the Ca

Indexed as

AnimalsAnxietyBehavior, AnimalCalciumCalcium Channels, L-TypeDisease Models, AnimalEukaryotic Initiation Factor-2Eukaryotic Initiation FactorsGenetic Predisposition to DiseaseHippocampusHumansMiceMice, KnockoutNeuronsProsencephalonPyramidal CellsCACNA1C protein, mouseCalciumCalcium Channels, L-TypeeIF-4BEukaryotic Initiation Factor-2Eukaryotic Initiation Factors

Identifiers

PMID28584287
PMCPMC5863913
OpenAlexW2621630739

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.