Evidence map›Paper›PMID 28584286›Full record

SynthesisMolecular psychiatry2018

Genome-wide meta-analysis of cognitive empathy: heritability, and correlates with sex, neuropsychiatric conditions and cognition.

V Warrier, K L Grasby, F Uzefovsky, R Toro, P Smith, B Chakrabarti, J Khadake, E Mawbey-Adamson, N Litterman, J-J Hottenga and 8 more

Open access · bronzeAbstract readMeta-Analysis
In one paragraph

Synthesis in Molecular psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 6 pooled it
14.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 6 syntheses or guidelines pooled it, 146 citations in OpenAlex.

  1. International journal of molecular sciences · 2025
    Pooled it
  2. Sex-stratified genome-wide meta-analysis identifies novel loci for cognitive decline in older adults.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Pooled it
  3. Pooled it
  4. Pooled it
  5. A meta-analytic investigation of grey matter differences in anorexia nervosa and autism spectrum disorder.European eating disorders review : the journal of the Eating Disorders Association · 2022
    Pooled it
  6. Pooled it
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  17. Sex and Gender in Population Neuroscience.Current topics in behavioral neurosciences · 2024
    Review
  18. Article
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 11 institutions in 6 countries.

V WarrierAutism Research Centre, Department of Psychiatry, University of Cambridge, Cambridgeshire, UK.
K L GrasbyQIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
F UzefovskyAutism Research Centre, Department of Psychiatry, University of Cambridge, Cambridgeshire, UK.
R ToroCNRS UMR 3571: Genes, Synapses and Cognition, Institut Pasteur, Paris, France.ORCID 0000-0002-6671-858X
P SmithAutism Research Centre, Department of Psychiatry, University of Cambridge, Cambridgeshire, UK.
B ChakrabartiCentre for Integrative Neuroscience and Neurodynamics, School of Psychology and Clinical Language Sciences, University of Reading, Reading, UK.ORCID 0000-0002-6649-7895
J KhadakeNIHR Cambridge BioResource, Cambridge University and Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
E Mawbey-AdamsonNIHR Cambridge BioResource, Cambridge University and Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
N Litterman23andMe Inc., Mountain View, CA, USA.
J-J HottengaDepartment of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
G LubkeDepartment of Psychology, University of Notre Dame, South Bend, IN, USA.
D I BoomsmaDepartment of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
N G MartinQIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
P K HatemiPolitical Science, Microbiology and Biochemistry, Pennsylvania State University, University Park, PA, USA.
S E MedlandQIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
D A Hinds23andMe Inc., Mountain View, CA, USA.
T BourgeronCNRS UMR 3571: Genes, Synapses and Cognition, Institut Pasteur, Paris, France.
S Baron-CohenAutism Research Centre, Department of Psychiatry, University of Cambridge, Cambridgeshire, UK.
QIMR Berghofer Medical Research Institute · AUUniversity of Cambridge · GB23andMe (United States) · USCambridge University Hospitals NHS Foundation Trust · GBCentre National de la Recherche Scientifique · FRAmsterdam Neuroscience · NLBen-Gurion University of the Negev · ILPennsylvania State University · USUniversity of Notre Dame · USUniversity of Reading · GBVrije Universiteit Amsterdam · NL

Funding

Development of a web-based database and research engine for genetic discoveryR44HG006981 · NHGRI · 23ANDME, INC. · PI MOUNTAIN, JOANNA L. · 2013 to 2014
$1.4M
Medical Research Council G0600977NHGRI NIH HHS R44 HG006981Wellcome Trust 091774
6 · The paper itself

Abstract

We conducted a genome-wide meta-analysis of cognitive empathy using the 'Reading the Mind in the Eyes' Test (Eyes Test) in 88,056 research volunteers of European Ancestry (44,574 females and 43,482 males) from 23andMe Inc., and an additional 1497 research volunteers of European Ancestry (891 females and 606 males) from the Brisbane Longitudinal Twin Study. We confirmed a female advantage on the Eyes Test (Cohen's d=0.21, P<2.2 × 10

Indexed as

AdultAgedAnorexia NervosaCognitionEmpathyFemaleGenetic Predisposition to DiseaseGenome-Wide Association StudyHumansMaleMental DisordersMiddle AgedPolymorphism, Single NucleotideSex FactorsTwinsWhite People

Identifiers

PMID28584286
PMCPMC5656177
OpenAlexW2951247507

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.