Evidence map›Paper›PMID 28584156›Full record

ArticleAntimicrobial agents and chemotherapy2017

Role of AxyZ Transcriptional Regulator in Overproduction of AxyXY-OprZ Multidrug Efflux System in Achromobacter Species Mutants Selected by Tobramycin.

Julien Bador, Catherine Neuwirth, Nadège Grangier, Marie Muniz, Leslie Germé, Jérémy Bonnet, Vignesh-Guru Pillay, Catherine Llanes, Claire de Curraize, Lucie Amoureux

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

  1. Epidemiology ofNew microbes and new infections · 2026
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  3. mSphere · 2026
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  7. Genetic and Biochemical Characterization of AXC-2 fromPathogens (Basel, Switzerland) · 2024
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  8. Article
  9. Article
  10. Review
  11. Microbial genomics · 2021
    Article
  12. Review
  13. Antimicrobial agents and chemotherapy · 2020
    Review
  14. Article
  15. Article
  16. Therapeutic advances in respiratory disease
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Julien BadorLaboratoire de Bactériologie, Hôpital Universitaire de Dijon, Dijon, France.
Catherine NeuwirthLaboratoire de Bactériologie, Hôpital Universitaire de Dijon, Dijon, France catherine.neuwirth@chu-dijon.fr.
Nadège GrangierLaboratoire de Bactériologie, Hôpital Universitaire de Dijon, Dijon, France.
Marie MunizLaboratoire de Bactériologie, Hôpital Universitaire de Dijon, Dijon, France.
Leslie GerméLaboratoire de Bactériologie, Hôpital Universitaire de Dijon, Dijon, France.
Jérémy BonnetLaboratoire de Bactériologie, Hôpital Universitaire de Dijon, Dijon, France.
Vignesh-Guru PillayLaboratoire de Bactériologie, Hôpital Universitaire de Dijon, Dijon, France.
Catherine LlanesUMR 6249 CNRS Chrono-environnement, Université de Bourgogne Franche-Comté, France.
Claire de CurraizeLaboratoire de Bactériologie, Hôpital Universitaire de Dijon, Dijon, France.
Lucie AmoureuxLaboratoire de Bactériologie, Hôpital Universitaire de Dijon, Dijon, France.
Centre Hospitalier Universitaire Dijon Bourgogne · FRLaboratoire Chrono-Environnement · FRCentre National de la Recherche Scientifique · FRUniversité de Bourgogne · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

AxyXY-OprZ is an RND-type efflux system that confers innate aminoglycoside resistance to

Indexed as

AchromobacterAmino Acid SequenceAmino Acid SubstitutionAnti-Bacterial AgentsBacterial Outer Membrane ProteinsBacterial ProteinsDrug Resistance, Multiple, BacterialGene DeletionGene Expression Regulation, BacterialHumansMembrane Transport ProteinsMicrobial Sensitivity TestsPseudomonas aeruginosaTobramycinTrans-ActivatorsAnti-Bacterial AgentsBacterial Outer Membrane ProteinsBacterial ProteinsMembrane Transport ProteinsMexXY protein, Pseudomonas aeruginosaTobramycinTrans-ActivatorsAchromobacterAxyXY-OprZAxyZcystic fibrosiseffluxtobramycin

Identifiers

PMID28584156
PMCPMC5527583
OpenAlexW2623953685

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.