ArticleAntimicrobial agents and chemotherapy2017
Targeted Metabolomics Analysis Identifies Intestinal Microbiota-Derived Urinary Biomarkers of Colonization Resistance in Antibiotic-Treated Mice.
Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 36 citations in OpenAlex.
- Mass spectrometry-based metabolomics for studying gut microbiota-derived metabolites in biological samples.Journal of food and drug analysis · 2026Review
- Identifying the Ratio of Circulating Cinnamoylglycine to Isoleucine as a Biomarker Linking Diet Quality, Microbial Metabolism, and Type 2 Diabetes Risk in the Coronary Artery Risk Development in Young Adults (CARDIA) Cohorts.The Journal of nutrition · 2026Article
- Longer durations of piperacillin/tazobactam treatment cause more prolonged alteration of colonization resistance in mice.PloS one · 2026Article
- Article
- Multi-Degree-of-Freedom Stretchable Metasurface Terahertz Sensor for Trace Cinnamoylglycine Detection.Biosensors · 2024Article
- Host microbiome depletion attenuates biofluid metabolite responses following radiation exposure.PloS one · 2024Article
- Bridging the Gap from Enterotypes to Personalized Dietary Recommendations: A Metabolomics Perspective on Microbiome Research.Metabolites · 2023Review
- Article
- Amino acids, microbiota-related metabolites, and the risk of incident diabetes among normoglycemic Chinese adults: Findings from the 4C study.Cell reports. Medicine · 2022Article
- Polyphenols and Small Phenolic Acids as Cellular Metabolic Regulators.Current issues in molecular biology · 2022Review
- Quantification of Gut Microbiota Dysbiosis-Related Organic Acids in Human Urine Using LC-MS/MS.Molecules (Basel, Switzerland) · 2022Article
- Small phenolic and indolic gut-dependent molecules in the primate central nervous system: levels vs. bioactivity.Metabolomics : Official journal of the Metabolomic Society · 2022Article
- Bacterial Metabolomics: Sample Preparation Methods.Biochemistry research international · 2022Review
- Urine metabolites for the identification of Onchocerca volvulus infections in patients from Cameroon.Parasites & vectors · 2021Article
- Serum metabolites reflecting gut microbiome alpha diversity predict type 2 diabetes.Gut microbes · 2020Article
- The Role of the Microbiota-Gut-Brain Axis and Antibiotics in ALS and Neurodegenerative Diseases.Microorganisms · 2020Review
- Profiling of polar urine metabolite extracts from Chinese colorectal cancer patients to screen for potential diagnostic and adverse-effect biomarkers.Journal of Cancer · 2020Article
- Metabolomics reveals elevated urinary excretion of collagen degradation and epithelial cell turnover products in irritable bowel syndrome patients.Metabolomics : Official journal of the Metabolomic Society · 2019Article
- Strain-Level Differentiation of Bacteria by Paper Spray Ionization Mass Spectrometry.Analytical chemistry · 2019Article
- Urinary Metabolites of Green Tea as Potential Markers of Colonization Resistance to Pathogenic Gut Bacteria in Mice.Pathogens & immunity · 2019Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Antibiotics excreted into the intestinal tract may disrupt the microbiota that provide colonization resistance against enteric pathogens and alter normal metabolic functions of the microbiota. Many of the bacterial metabolites produced in the intestinal tract are absorbed systemically and excreted in urine. Here, we used a mouse model to test the hypothesis that alterations in levels of targeted bacterial metabolites in urine specimens could provide useful biomarkers indicating disrupted or intact colonization resistance. To assess
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.