Evidence map›Paper›PMID 28584135›Full record

ArticleBlood2017

Genome-wide association study to identify variants associated with acute severe vaso-occlusive pain in sickle cell anemia.

Shruti Chaturvedi, Pallav Bhatnagar, Christopher J Bean, Martin H Steinberg, Jaqueline N Milton, James F Casella, Emily Barron-Casella, Dan E Arking, Michael R DeBaun

Open access · bronzeAbstract readLetter
In one paragraph

Article in Blood, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Fetal hemoglobin modulates neurocognitive performance in sickle cell anemiaCurrent research in translational medicine · 2022
    Article
  13. Article
  14. Biomarker signatures of sickle cell disease severity.Blood cells, molecules & diseases · 2018
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Shruti ChaturvediDivision of Hematology and Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN.ORCID 0000-0001-6832-2389
Pallav BhatnagarMcKusick-Nathans Institute of Genetic Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD.
Christopher J BeanDivision of Blood Disorders, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA.
Martin H SteinbergDepartment of Medicine.
Jaqueline N MiltonDepartment of Biostatistics, Boston University School of Public Health, Boston, MA.
James F CasellaDivision of Pediatric Hematology, Department of Pediatrics, School of Medicine, Johns Hopkins University, Baltimore, MD; and.
Emily Barron-CasellaDivision of Pediatric Hematology, Department of Pediatrics, School of Medicine, Johns Hopkins University, Baltimore, MD; and.
Dan E ArkingMcKusick-Nathans Institute of Genetic Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD.
Michael R DeBaunDepartment of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN.
Johns Hopkins University · USBoston University · USCenters for Disease Control and Prevention · USVanderbilt University · USVanderbilt University Medical Center · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Epistasis, GeneticGenetic VariationPolymorphism, Single NucleotideAcute PainAdolescentAnemia, Sickle CellArterial Occlusive DiseasesBlack PeopleChildChild, PreschoolChromosomes, Human, Pair 4FemaleFetal HemoglobinGenome-Wide Association StudyGenotyping TechniquesHumansFetal Hemoglobin

Identifiers

PMID28584135
PMCPMC5542853
OpenAlexW2622120482

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.