ArticleBrazilian journal of physical therapy
Resistance training improves aortic structure in Wistar rats.
Article in Brazilian journal of physical therapy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.
- Muscle hypertrophy and ladder-based resistance training for rodents: A systematic review and meta-analysis.Physiological reports · 2020Pooled it
- Weighted cart pull: A novel outcome measure for sustained motor function in mice.Experimental physiology · 2025Article
- Resistance- and endurance-trained young men display comparable carotid artery strain parameters that are superior to untrained men.European journal of applied physiology · 2025Article
- Exercise protects vascular function by countering senescent cells in older adults.Frontiers in physiology · 2023Review
- Animal Models of Exercise From Rodents to Pythons.Circulation research · 2022Review
- Long-term exercise results in morphological and biomechanical changes in coronary resistance arterioles in male and female rats.Biology of sex differences · 2020Article
- Cardiovascular Adaptations Induced by Resistance Training in Animal Models.International journal of medical sciences · 2018Review
- Research Progress of Oxidative Stress and MicroRNAs in the Prevention of Catheter-Related Thrombus Under Resistance Exercise.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisArticle
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLittle information is available on the effects of resistance training on the aortic wall.
objectiveThis study aimed to quantify the effects of a resistance-training program on blood pressure and aortic wall structural components.
methodsRats (aged three months) were randomized into sedentary group (control group, CG; n=10) or trained group (TG; n=10). The TG rats performed resistance training by climbing a 1.1-m vertical ladder (80° incline) five times a week for 12 weeks, and the CG remained sedentary. The rats were sacrificed and 5mm of the ascending aorta was submitted to histological sections, which were stained with hematoxylin-eosin, Picrosirius red, and Verhoeff's elastin, and used for morphometric studies. Left ventricle (LV) hypertrophy was determined by measuring LV wall thickness and LV internal diameter.
resultsThe rats had similar repetition maximum before the resistance training. At the end of the resistance training period, the repetition maximum of the TG was 3.04-fold greater than the body weight. In the twelfth month, the left ventricular weight was 15.3% larger in the TG than in the CG, and the left ventricular internal diameter was reduced by 10% in the TG. Rats exposed to resistance training had a significant increase in aortic wall thickness, in both elastic lamina and collagen fibers, and in the thickness of collagen fibrils.
conclusionResistance training induces the development of concentric cardiac hypertrophy and improves the aortic wall components by producing a morphological expression pattern distinct from aortic pathological adaptation.
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