ReviewAnnals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology2017
The case for impulse oscillometry in the management of asthma in children and adults.
Review in Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 51 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy of Mepolizumab in Patients With Late-onset Severe Eosinophilic Asthma and Fixed Obstruction
THREAT: Testing Harms Related to Exposure to Allergenic and Epithelial Toxins
Who cites it
51 citing papers in PubMed, 2 syntheses or guidelines pooled it, 165 citations in OpenAlex.
- The predictive value of impulse oscillometry for asthma exacerbations in childhood: A systematic review and meta-analyses.Pediatric pulmonology · 2021Pooled it
- Non-malignant respiratory disease among workers in the rubber manufacturing industry: A systematic review and meta-analysis.American journal of industrial medicine · 2019Pooled it
- Small Airway Dysfunction Assessed by Impulse Oscillometry in Children with Congenital Adrenal Hyperplasia: A Preliminary Case-Control Study.Journal of clinical medicine · 2026Article
- Small Airway Dysfunction Assessed by Impulse Oscillometry in Non-Asthmatic Children with Moderate-to-Severe Persistent Allergic Rhinitis During the Early Phase of Allergen Immunotherapy.Journal of clinical medicine · 2026Article
- Comparing Changes in FEVJournal of clinical medicine · 2026Article
- Real-life application of respiratory oscillometry in pediatric asthma outpatient care: Feasibility and methodological aspects.Physiological reports · 2026Article
- Impulse oscillometry values calibrated against spirometric obstruction in children with suspected asthma.Frontiers in pediatrics · 2026Article
- Bronchodilator Response of TEV/FEV3 and Its Implications in Pediatric Asthma.Allergy, asthma & immunology research · 2025Article
- Assessment of ventilation heterogeneity and particle deposition in asthmatics using combined SPECT/CT imaging and computational modeling approaches.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences · 2025Article
- The influence of obesity on IOS parameters in asthma, COPD, and other lung diseases: analyzed by random forest.BMC pulmonary medicine · 2025Article
- Review
- Changes in Small Airway Physiology Measured by Impulse Oscillometry in Subjects with Allergic Asthma Following Methacholine and Inhaled Allergen Challenge.Journal of clinical medicine · 2025Article
- Detection of Inadequately Controlled Asthma in Adults Using Impulse Oscillometry and Fractional Exhaled Nitric Oxide.Journal of asthma and allergy · 2025Article
- Managing Small Airways Dysfunction in COPD Patients in Real Life Under Fixed Triple Combination of Beclomethasone/Formoterol/Glycopyrronium: The MASCOT Real World Evidence Study.International journal of chronic obstructive pulmonary disease · 2025Observational
- Total immunoglobulin E levels in induced sputum reflect asthma control status.Clinical and translational allergy · 2025Article
- Application of Impulse Oscillometry Combined with Fractional Exhaled Nitric Oxide in Monitoring Asthma Control Levels in Children.Journal of asthma and allergy · 2025Article
- Oscillometry Assesses Small Airway Disease and Reveals Peripheral Lung Pathology in Early Pulmonary Fibrosis: A Cross-Sectional Study.Diagnostics (Basel, Switzerland) · 2024Article
- Vaping causes an acute BMI-dependent change in pulmonary blood flow.Physiological reports · 2024Article
- Bronchodilator response assessment through impulse oscillometry system and spirometry in children and adolescents with cystic fibrosis.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2024Article
- Impulse oscillometry indices in relation to respiratory symptoms and spirometry in the Swedish Cardiopulmonary Bioimage Study.ERJ open research · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 5 institutions in 2 countries.
Funding
Abstract
objectiveTo provide a clinical rationale for including impulse oscillometry (IOS) as a part of standard office-based asthma assessment. DATA SOURCES: PubMed and Google search, limited to English language and human disease, with the keywords IOS and asthma. STUDY SELECTIONS: Articles included in this review were based on the expert opinion and previous publications by the authors.
resultsIn children, IOS was more useful than spirometry in identifying asthma and uncontrolled asthma and predicting loss of control and exacerbations. IOS predicts young children at risk for loss of lung function with age and the potential for early intervention to prevent further sequelae. In adults, peripheral airway impairment detected by IOS or spirometry (ie, forced expiratory flow between 25% and 75%) commonly occurs across severity, and each measure may be complementary in predicting loss of control even with normal forced expiratory volume in 1 second. Extrafine inhaled corticosteroids with or without long-acting β-agonists proved superior to standard particle aerosols in improving IOS-detected peripheral airway obstruction. Our data also suggest that currently available commercial reference values for lung resistance at 5 Hz and lung reactance at 5 Hz are applicable across diverse populations, but further studies are needed.
conclusionThe findings of this review suggest that IOS can add value to traditional clinical and spirometric assessment and thus improve management of asthma in children and adults, as well as have the potential to detect early dysfunction of the peripheral airways, which may result in better outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.