Evidence map›Paper›PMID 28582513›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2017

Evidence of Ebola Virus Replication and High Concentration in Semen of a Patient During Recovery.

Kayla G Barnes, Jason Kindrachuk, Aaron E Lin, Shirlee Wohl, James Qu, Samantha D Tostenson, William R Dorman, Michele Busby, Katherine J Siddle, Cynthia Y Luo and 4 more

Open access · hybridAbstract readCase Reports
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
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  4. Molecular determinants of cross-species transmission in emerging viral infections.Microbiology and molecular biology reviews : MMBR · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 1 country.

Kayla G BarnesCenter for Systems Biology, Harvard University, Boston, Massachusetts.
Jason KindrachukCritical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda.
Aaron E LinCenter for Systems Biology, Harvard University, Boston, Massachusetts.
Shirlee WohlCenter for Systems Biology, Harvard University, Boston, Massachusetts.
James QuBroad Institute of MIT and Harvard, Cambridge, Massachusetts.
Samantha D TostensonDiagnostic Systems Division, US Army Medical Research Institute of Infectious Diseases, Frederick.
William R DormanDiagnostic Systems Division, US Army Medical Research Institute of Infectious Diseases, Frederick.
Michele BusbyBroad Institute of MIT and Harvard, Cambridge, Massachusetts.
Katherine J SiddleCenter for Systems Biology, Harvard University, Boston, Massachusetts.
Cynthia Y LuoCenter for Systems Biology, Harvard University, Boston, Massachusetts.
Christian B MatrangaCenter for Systems Biology, Harvard University, Boston, Massachusetts.
Richard T DaveyNational Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.
Pardis C SabetiCenter for Systems Biology, Harvard University, Boston, Massachusetts.
Daniel S ChertowCritical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda.
Broad Institute · USCenter for Systems Biology · USHarvard University · USNational Institutes of Health · USUnited States Army Medical Research Institute of Infectious Diseases · USNational Institutes of Health Clinical Center · US

Funding

Viral Genomics: evolution, spread, and host interactionsU19AI110818 · NIAID · BROAD INSTITUTE, INC. · PI CUOMO, CHRISTINA A · 2014 to 2024
$66.5M
Influenza and Emerging Infectious DiseasesZIAAI000984 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI DAVEY, RICHARD · 2009 to 2025
$44.1M
Clinical and Molecular Features of Ebola Virus DiseaseZIACL009024 · CLC · CLINICAL CENTER · PI CHERTOW, DANIEL S · 2017 to 2025
$0k
NIAID NIH HHS U19 AI110818
6 · The paper itself

Abstract

In one patient over time, we found that concentration of Ebola virus RNA in semen during recovery is remarkably higher than blood at peak illness. Virus in semen is replication-competent with no change in viral genome over time. Presence of sense RNA suggests replication in cells present in semen.

Indexed as

AdultEbolavirusGenome, ViralHemorrhagic Fever, EbolaHumansMaleRNA, ViralSemenViral LoadRNA, ViralEbolapersistencereplicationsemensexual transmission

Identifiers

PMID28582513
PMCPMC5850519
OpenAlexW2620979759

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.