Evidence map›Paper›PMID 28582496›Full record

ArticlePathogens and disease2017

Vaginal Candida spp. genomes from women with vulvovaginal candidiasis.

L Latéy Bradford, Marcus C Chibucos, Bing Ma, Vincent Bruno, Jacques Ravel

Open access · bronzeAbstract read
In one paragraph

Article in Pathogens and disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Guideline
  2. Review
  3. Review
  4. Article
  5. Article
  6. Oral Intake of the Commercial Probiotic Blend SynbioJournal of clinical medicine · 2022
    Article
  7. Article
  8. Review
  9. Review
  10. Pathogenesis and Clinical Relevance ofFrontiers in microbiology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

L Latéy BradfordDepartment of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201 USA.
Marcus C ChibucosDepartment of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201 USA.
Bing MaDepartment of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201 USA.
Vincent BrunoDepartment of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201 USA.
Jacques RavelDepartment of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201 USA.
University of Maryland, Baltimore · US

Funding

EXPAND PARTICIPATION BY MINORITIES IN BIOMEDICAL SCIENCER25GM055036 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE COUNTY · PI SUMMERS, MICHAEL FINLEY · 1996 to 2021
$16.9M
The Microbial Ecology of Bacterial Vaginosis: A Fine Scale Resolution MetagenomicUH2AI083264 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI RAVEL, JACQUES · 2009 to 2011
$1.9M
Dynamics in the Vaginal Ecosystem and Development of Vulvovaginal CandidiasisF31AI116023 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI BRADFORD, L. LATÉY · 2016 to 2017
$65k
NIAID NIH HHS F31 AI116023NIAID NIH HHS UH2 AI083264NIGMS NIH HHS R25 GM055036
6 · The paper itself

Abstract

Candida albicans is the predominant cause of vulvovaginal candidiasis (VVC). Little is known regarding the genetic diversity of Candida spp. in the vagina or the microvariations in strains over time that may contribute to the development of VVC. This study reports the draft genome sequences of four C. albicans and one C. glabrata strains isolated from women with VVC. An SNP-based whole-genome phylogeny indicates that these isolates are closely related; however, phylogenetic distances between them suggest that there may be genetic adaptations driven by unique host environments. These sequences will facilitate further comparative analyses and ultimately improve our understanding of genetic variation in isolates of Candida spp. that are associated with VVC.

Indexed as

Genome, FungalPhylogenyAdultAntifungal AgentsCandida albicansCandida glabrataCandidiasis, VulvovaginalFemaleGenetic VariationHumansLongitudinal StudiesVaginaWhole Genome SequencingAntifungal AgentsCandida albicansCandida glabrataclinical isolatessingle nucleotide polymorphisms (SNP)yeast infection

Identifiers

PMID28582496
PMCPMC5827580
OpenAlexW2620814342

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.