ReviewCurrent opinion in infectious diseases2017
Outbreaks in the neonatal ICU: a review of the literature.
Review in Current opinion in infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Investigating the implementation of infection prevention and control practices in neonatal care across country income levels: a systematic review.Antimicrobial resistance and infection control · 2025Pooled it
- Extended spectrum beta-lactamase Klebsiella pneumoniae (ESBL-KP) bloodstream infection outbreak in a Neonatal Intensive Care Unit (NICU) in Bangui, Central African Republic (CAR).Antimicrobial resistance and infection control · 2026Article
- Healthcare-associated infections in Chinese neonates: a multicenter retrospective period prevalence survey in Jiangsu Province (2023).BMC infectious diseases · 2026Article
- Ecological dynamics of three persistent opportunistic pathogens in hospital sinks and their potential antagonistic bacteria.mSystems · 2026Article
- Whole-genome sequencing reveals a unique outbreak of methicillin-resistantInfection prevention in practice · 2026Article
- Molecular Relatedness of Maternal and Neonatal Multidrug-Resistant Gram-Negative Colonization Isolates in Low- and Middle-Income Countries: A Systematic Review.Open forum infectious diseases · 2026Review
- Article
- Respiratory Syncytial Virus and US Pediatric Intensive Care Utilization.JAMA network open · 2024Article
- Outbreaks in the Neonatal Intensive Care Unit: Description and Management.Tropical medicine and infectious disease · 2024Review
- Rapid identification and subsequent contextualization of an outbreak of methicillin-resistantMicrobial genomics · 2024Article
- Cultivation and sequencing-free protocol foriScience · 2024Article
- Linking preterm infant gut microbiota to nasograstric enteral feeding tubes: exploring potential interactions and microbial strain transmission.Frontiers in pediatrics · 2024Article
- Using adenosine triphosphate bioluminescence level monitoring to identify bacterial reservoirs during two consecutive Enterococcus faecium and Staphylococcus capitis nosocomial infection outbreaks at a neonatal intensive care unit.Antimicrobial resistance and infection control · 2023Article
- Maternal Colonization Versus Nosocomial Transmission as the Source of Drug-Resistant Bloodstream Infection in an Indian Neonatal Intensive Care Unit: A Prospective Cohort Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023Article
- Infant isolation and cohorting for preventing or reducing transmission of healthcare-associated infections in neonatal units.The Cochrane database of systematic reviews · 2023Review
- Article
- Epidemiology of nosocomialIranian journal of microbiology · 2023Article
- Serratia marcescens Colonization in a Neonatal Intensive Care Unit Has Multiple Sources, with Sink Drains as a Major Reservoir.Applied and environmental microbiology · 2023Article
- Prospective Genomic Surveillance Reveals Cryptic MRSA Outbreaks with Local to International Origins among NICU Patients.Journal of clinical microbiology · 2023Article
- Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
purpose of reviewNeonates in the neonatal ICU (NICU) are uniquely vulnerable to colonization and infection with pathogens such as multidrug resistant Gram-negative bacteria, which in turn are associated with increased infection-related morbidities and higher case-fatality rates. We reviewed the English, French, and German language literature published between 2015 and 2017, for reports of NICU outbreaks. RECENT
findingsA total of 39 outbreaks in NICUs were reported with Gram-negative bacteria (n = 21; 54%) causing most, and extended spectrum beta-lactamase-producing organisms being the most frequent resistance mechanism reported (n = 5). Five viral outbreaks were reported (respiratory syncytial virus = 3). A significant proportion of outbreaks (33%) did not identify a source. Whole genome sequencing was used more (n = 6 reports). The most common described infection prevention and control interventions included staff and parent education on hand hygiene, patient isolation, additional contact precautions, including discontinuation of 'kangaroo care', and cohorting. Reporting and publication bias are likely common. SUMMARY: NICUs must be vigilant in identifying outbreaks, conduct comprehensive investigations, and implement targeted infection prevention and control strategies. Molecular epidemiology capacities are an essential element in outbreak investigation. More studies are needed to determine the added value of active colonization screening and their impact on outbreak development.
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