Evidence map›Paper›PMID 28581909›Full record

ReviewBioengineered2017

Development of CRISPR/Cas9 mediated virus resistance in agriculturally important crops.

Surender Khatodia, Kirti Bhatotia, Narendra Tuteja

Open access · goldAbstract readReview
In one paragraph

Review in Bioengineered, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 54 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
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  7. Review
  8. Genome Editing of RiceViruses · 2021
    Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
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  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Surender Khatodiaa Amity Institute of Biotechnology, Amity University Haryana , Gurgaon , India.ORCID http://orcid.org/0000-0002-5764-8444
Kirti Bhatotiaa Amity Institute of Biotechnology, Amity University Haryana , Gurgaon , India.
Narendra Tutejab Amity Institute of Microbial Technology, Amity University , Noida , India.
Amity University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clustered regulatory interspaced short palindromic repeats (CRISPR)/CRISPR associated nuclease 9 (Cas9) system of targeted genome editing has already revolutionized the plant science research. This is a RNA guided programmable endonuclease based system composed of 2 components, the Cas9 nuclease and an engineered guide RNA targeting any DNA sequence of the form N20-NGG for novel genome editing applications. The CRISPR/Cas9 technology of targeted genome editing has been recently applied for imparting virus resistance in plants. The robustness, wide adaptability, and easy engineering of this system has proved its potential as an antiviral tool for plants. Novel DNA free genome editing by using the preassembled Cas9/gRNA ribonucleoprotein complex for development of virus resistance in any plant species have been prospected for the future. Also, in this review we have discussed the reports of CRISPR/Cas9 mediated virus resistance strategy against geminiviruses by targeting the viral genome and transgene free strategy against RNA viruses by targeting the host plant factors. In conclusion, CRISPR/Cas9 technology will provide a more durable and broad spectrum viral resistance in agriculturally important crops which will eventually lead to public acceptance and commercialization in the near future.

Indexed as

Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Associated ProteinsCRISPR-Cas SystemsCrops, AgriculturalEndonucleasesGene EditingGenetic EnhancementPlant DiseasesPlants, Genetically ModifiedPlant VirusesCRISPR-Associated ProteinsEndonucleasesCRISPR/Cas9DNA free editingplantsRNPvirus resistance

Identifiers

PMID28581909
PMCPMC5470520
OpenAlexW2591184030

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.