Evidence map›Paper›PMID 28581265›Full record

ArticleJournal of Korean medical science2017

High Maternal Blood Mercury Level Is Associated with Low Verbal IQ in Children.

Kyoung Sook Jeong, Hyewon Park, Eunhee Ha, Jiyoung Shin, Yun Chul Hong, Mina Ha, Hyesook Park, Bung Nyun Kim, Boeun Lee, Soo Jeong Lee and 3 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Journal of Korean medical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 3 pooled it
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. A Call for Training Pediatric Practitioners About Industrial Chemicals and Child Health.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Neurodevelopmental Effects of Mercury.Advances in neurotoxicology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Kyoung Sook JeongDepartment of Occupational and Environmental Medicine, Dongguk University College of Medicine, Dongguk University Ilsan Hospital, Goyang, Korea.ORCID https://orcid.org/0000-0002-6897-8289
Hyewon ParkDepartment of Child and Family Welfare, University of Ulsan, Ulsan, Korea.ORCID https://orcid.org/0000-0003-2074-6128
Eunhee HaDepartment of Occupational and Environmental Medicine and Medical Research Center, Ewha Womans University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-4224-3858
Jiyoung ShinDepartment of Occupational and Environmental Medicine and Medical Research Center, Ewha Womans University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-8099-2120
Yun Chul HongInstitute of Environmental Medicine, Medical Research Center, Seoul National University, Seoul, Korea.ORCID https://orcid.org/0000-0001-9010-7271
Mina HaDepartment of Preventive Medicine, Dankook University College of Medicine, Cheonan, Korea.ORCID https://orcid.org/0000-0003-1011-9446
Hyesook ParkDepartment of Preventive Medicine and Medical Research Center, Ewha Womans University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-9359-6522
Bung Nyun KimDepartment of Psychiatry, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-2403-3291
Boeun LeeMonitoring and Analysis Division, Han River Basin Environmental Office, Hanam, Korea.ORCID https://orcid.org/0000-0002-9032-9656
Soo Jeong LeeDepartment of Obstetrics and Gynecology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea.ORCID https://orcid.org/0000-0001-9272-6770
Kyung Yeon LeeDepartment of Pediatrics, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea.ORCID https://orcid.org/0000-0001-6821-1056
Ja Hyeong KimDepartment of Pediatrics, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea.ORCID https://orcid.org/0000-0003-0691-1924
Yangho KimDepartment of Occupational and Environmental Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea. yanghokm@nuri.net.ORCID https://orcid.org/0000-0002-6462-0829
Ulsan College · KREwha Womans University Medical Center · KRSeoul National University · KRDankook University · KRDongguk University Ilsan Hospital · KRHanshin University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of the present study was to investigate the relationship of IQ in children with maternal blood mercury concentration during late pregnancy. The present study is a component of the Mothers and Children's Environmental Health (MOCEH) study, a multi-center birth cohort project in Korea that began in 2006. The study cohort consisted of 553 children whose mothers underwent testing for blood mercury during late pregnancy. The children were given the Korean language version of the Wechsler Preschool and Primary Scale of Intelligence, revised edition (WPPSI-R) at 60 months of age. Multivariate linear regression analysis, with adjustment for covariates, was used to assess the relationship between verbal, performance, and total IQ in children and blood mercury concentration of mothers during late pregnancy. The results of multivariate linear regression analysis indicated that a doubling of blood mercury was associated with the decrease in verbal and total IQ by 2.482 (95% confidence interval [CI], 0.749-4.214) and 2.402 (95% CI, 0.526-4.279), respectively, after adjustment. This inverse association remained after further adjustment for blood lead concentration. Fish intake is an effect modifier of child IQ. In conclusion, high maternal blood mercury level is associated with low verbal IQ in children.

Indexed as

Child DevelopmentChild, PreschoolCohort StudiesDietFemaleHumansIntelligenceIntelligence TestsMaleMercuryPregnancySeafoodMercuryBlood LeadBlood MercuryFishIQWPPSI-R

Identifiers

PMID28581265
PMCPMC5461312
OpenAlexW2623627987

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.