ArticleNature communications2017
Extra-embryonic tissue spreading directs early embryo morphogenesis in killifish.
Article in Nature communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 52 citations in OpenAlex.
- Coping with uncertainty: Challenges for robust pattern formation in dynamical tissues.Seminars in cell & developmental biology · 2025Review
- Article
- Axis formation in annual killifish: Nodal and β-catenin regulate morphogenesis without Huluwa prepatterning.Science (New York, N.Y.) · 2024Article
- Immunohistochemical characterisation of the adult Nothobranchius furzeri intestine.Cell and tissue research · 2024Article
- Directional Cell Migration Guided by a Strain Gradient.Small (Weinheim an der Bergstrasse, Germany) · 2024Article
- Insight to motor clutch model for sensing of ECM residual strain.Mechanobiology in medicine · 2023Article
- Protocol for extracting live blastoderm cells from embryos of annual killifish.STAR protocols · 2023Article
- A computational framework for testing hypotheses of the minimal mechanical requirements for cell aggregation using early annual killifish embryogenesis as a model.Frontiers in cell and developmental biology · 2023Article
- Origin, form and function of extraembryonic structures in teleost fishes.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Review
- The unappreciated generative role of cell movements in pattern formation.Royal Society open science · 2022Review
- Article
- Differential Cellular Stiffness Contributes to Tissue Elongation on an Expanding Surface.Frontiers in cell and developmental biology · 2022Article
- Geometrical characterization of active contraction pulses in epithelial cells using the two-dimensional vertex model.Journal of the Royal Society, Interface · 2022Article
- Article
- Maternally regulated gastrulation as a source of variation contributing to cavefish forebrain evolution.eLife · 2019Article
- Cell cycle dynamics during diapause entry and exit in an annual killifish revealed by FUCCI technology.EvoDevo · 2019Article
- Lipid rafts regulate the lamellipodia formation of melanoma A375 cells via actin cytoskeleton-mediated recruitment of β1 and β3 integrin.Oncology letters · 2018Article
- Article
- E-cadherin expression pattern during zebrafish embryonic epidermis development.F1000Research · 2018Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The spreading of mesenchymal-like cell layers is critical for embryo morphogenesis and tissue repair, yet we know little of this process in vivo. Here we take advantage of unique developmental features of the non-conventional annual killifish embryo to study the principles underlying tissue spreading in a simple cellular environment, devoid of patterning signals and major morphogenetic cell movements. Using in vivo experimentation and physical modelling we reveal that the extra-embryonic epithelial enveloping cell layer, thought mainly to provide protection to the embryo, directs cell migration and the spreading of embryonic tissue during early development. This function relies on the ability of embryonic cells to couple their autonomous random motility to non-autonomous signals arising from the expansion of the extra-embryonic epithelium, mediated by cell membrane adhesion and tension. Thus, we present a mechanism of extra-embryonic control of embryo morphogenesis that couples the mechanical properties of adjacent tissues in the early killifish embryo.
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