Evidence map›Paper›PMID 28580513›Full record

ArticleJournal of assisted reproduction and genetics2017

Cumulative live birth and surplus embryo incidence after frozen-thaw cycles in PCOS: how many oocytes do we need?

Yuan-Hui Chen, Qian Wang, Ya-Nan Zhang, Xiao Han, Dong-Han Li, Cui-Lian Zhang

Open access · bronzeAbstract read
In one paragraph

Article in Journal of assisted reproduction and genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Review
  3. Too many embryos: a critical perspective on a global challenge.Journal of assisted reproduction and genetics · 2024
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  9. World journal of clinical cases · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yuan-Hui ChenReproductive Medical Center, Henan Provincial People's Hospital, Weiwu Road, Zhengzhou, 450003, Henan Province, People's Republic of China.
Qian WangReproductive Medical Center, Henan Provincial People's Hospital, Weiwu Road, Zhengzhou, 450003, Henan Province, People's Republic of China.
Ya-Nan ZhangReproductive Medical Center, Henan Provincial People's Hospital, Weiwu Road, Zhengzhou, 450003, Henan Province, People's Republic of China.
Xiao HanReproductive Medical Center, Henan Provincial People's Hospital, Weiwu Road, Zhengzhou, 450003, Henan Province, People's Republic of China.
Dong-Han LiReproductive Medical Center, Henan Provincial People's Hospital, Weiwu Road, Zhengzhou, 450003, Henan Province, People's Republic of China.
Cui-Lian ZhangReproductive Medical Center, Henan Provincial People's Hospital, Weiwu Road, Zhengzhou, 450003, Henan Province, People's Republic of China. luckyzcl@qq.com.
Zhengzhou University · CNHenan Provincial People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to evaluate the cumulative live birth rate (CLBR) and surplus embryo rate of polycystic ovarian syndrome (PCOS) patients during in vitro fertilization and embryo transfer (IVF-ET) treatment.

methodsIn this retrospective cohort study, we analyzed 1142 PCOS patients who underwent first IVF in our institution between January 2011 and December 2014. All patients were categorized into five groups according to the number of oocytes retrieved. Main outcomes include CLBR and surplus embryo rate.

resultsA strong correlation was observed between number of oocytes retrieved and CLBR as well as surplus embryo rate in PCOS patients. CLBR was elevated with the increasing number of oocytes and plateaued when oocyte number was up to ten, whereas the surplus embryo rate steadily increased in line with the increase of oocyte number. Patients transferred with frozen embryos showed higher CLBR and LBR during first ET than patients transferred with fresh embryos.

conclusionsFor PCOS patients, retrieving more than ten oocytes leads to no significant benefit to CLBR but generates surplus embryos. Thus, moderate ovarian stimulation should be reconsidered during IVF treatment.

Indexed as

Fertilization in VitroBirth RateEmbryo TransferFemaleHumansLive BirthOocyte RetrievalOocytesPolycystic Ovary SyndromePregnancyPregnancy OutcomePregnancy RateSperm Injections, IntracytoplasmicCumulative live birth ratePolycystic ovarian syndromeSurplus embryo rate

Identifiers

PMID28580513
PMCPMC5581780
OpenAlexW2620881638

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.