Evidence map›Paper›PMID 28580460›Full record

ArticleProceedings of the IFAC World Congress. International Federation of Automatic Control. World Congress2014

State Estimation with Sensor Recalibrations and Asynchronous Measurements for MPC of an Artificial Pancreas to Treat T1DM.

Ravi Gondhalekar, Eyal Dassau, Francis J Doyle

Abstract read
In one paragraph

Article in Proceedings of the IFAC World Congress. International Federation of Automatic Control. World Congress, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Velocity-weighting & velocity-penalty MPC of an artificial pancreas: Improved safety & performance.Automatica : the journal of IFAC, the International Federation of Automatic Control · 2018
    Article
  2. Moving-horizon-like state estimation via continuous glucose monitor feedback in MPC of an artificial pancreas for type 1 diabetes.Proceedings of the ... IEEE Conference on Decision & Control. IEEE Conference on Decision & Control · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ravi GondhalekarDept. Chemical Engineering, University of California Santa Barbara (UCSB), USA.
Eyal DassauDept. Chemical Engineering, University of California Santa Barbara (UCSB), USA.
Francis J DoyleDept. Chemical Engineering, University of California Santa Barbara (UCSB), USA.

Funding

Ambulatory Artificial Pancreas: merging physiology, behavior, and control designDP3DK094331 · NIDDK · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI BASU, ANANDA, DOYLE, FRANCIS J · 2011 to 2014
$4.6M
Closed-loop Artificial Pancreas: Algorithm Engineering and Clinical EvaluationR01DK085628 · NIDDK · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI DOYLE, FRANCIS J, JOVANOVIC, LOIS · 2009 to 2013
$3.4M
NIDDK NIH HHS DP3 DK094331NIDDK NIH HHS R01 DK085628
6 · The paper itself

Abstract

A novel state estimation scheme is proposed for use in Model Predictive Control (MPC) of an artificial pancreas based on Continuous Glucose Monitor (CGM) feedback, for treating type 1 diabetes mellitus. The performance of MPC strategies heavily depends on the initial condition of the predictions, typically characterized by a state estimator. Commonly employed Luenberger-observers and Kalman-filters are effective much of the time, but suffer limitations. Three particular limitations are tackled by the proposed approach. First, CGM recalibrations, step changes that cause highly dynamic responses in recursive state estimators, are accommodated in a graceful manner. Second, the proposed strategy is not affected by CGM measurements that are asynchronous, i.e., neither of fixed sample-period, nor of a sample-period that is equal to the controller's. Third, the proposal suffers no offsets due to plant-model mismatches. The proposed approach is based on moving-horizon optimization.

Indexed as

Artificial pancreasModel predictive controlOptimizationState estimation

Identifiers

PMID28580460
PMCPMC5451162

What OpenQuestion holds

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LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.