Evidence map›Paper›PMID 28580456›Full record

ArticleJournal of family medicine2016

Predictors of Adherence to Nicotine Replacement Therapy (Nicotine Patch) Among Homeless Persons Enrolled in a Randomized Controlled Trial Targeting Smoking Cessation.

O Ojo-Fati, J L Thomas, R I Vogel, O Ogedegbe, G Jean-Louis, K S Okuyemi

Registry-linked trialAbstract read
In one paragraph

Article in Journal of family medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00786149 (Improving Varenicline Adherence and Outcomes in Homeless Smokers), which is not on this map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00786149 phase3completednot on this map

Improving Varenicline Adherence and Outcomes in Homeless Smokers

TypeinterventionalSponsorUniversity of MinnesotaRan2007 to 2011Enrolled428ConditionsTobacco Use CessationArmsVarenicline plus Motivational Interviewing counseling, Varenicline without counseling
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Interventions to reduce tobacco use in people experiencing homelessness.The Cochrane database of systematic reviews · 2020
    Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Predictors of Nicotine Replacement Therapy Adherence: Mixed-Methods Research With a Convergent Parallel Design.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Motivational interviewing for smoking cessation.The Cochrane database of systematic reviews · 2019
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

O Ojo-FatiDepartment of Family Medicine and Community Health, University of Minnesota, Minneapolis, MN, USA.
J L ThomasProgram in Health Disparities Research, University Of Minnesota, Minneapolis, MN, USA.
R I VogelMasonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.
O OgedegbeDepartment of Population Health, New York University School of Medicine, New York, NY, USA.
G Jean-LouisDepartment of Population Health, New York University School of Medicine, New York, NY, USA.
K S OkuyemiDepartment of Family Medicine and Community Health, University of Minnesota, Minneapolis, MN, USA.

Funding

Women's CancerP30CA077598 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Timothy C. Hallstrom · 1998 to 2026
$100.4M
University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR000114 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R · 2012 to 2015
$35.0M
University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR002494 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R, WEISDORF, DANIEL J · 2018 to 2022
$34.9M
Improving Varenicline Adherence and Outcome in Homeless SmokersR01HL081522 · NHLBI · UNIVERSITY OF UTAH · PI OKUYEMI, KOLAWOLE S · 2007 to 2018
$6.4M
NCATS NIH HHS UL1 TR000114NCATS NIH HHS UL1 TR002494NCI NIH HHS P30 CA077598NHLBI NIH HHS R01 HL081522
6 · The paper itself

Abstract

introductionAdherence to smoking cessation treatment is generally low, especially among socio-economically disadvantaged groups including individuals experiencing homelessness and those with mental illnesses. Despite the high smoking rates in homeless populations (~70%) no study to date has systematically examined predictors of adherence to nicotine replacement therapy (NRT) in this population.

objectiveThe aim of this secondary analysis was to identify predictors of adherence to NRT in a smoking cessation trial conducted among homeless smokers.

methodsSecondary analysis of data from a randomized controlled trial enrolling 430 persons who were homeless and current cigarette smokers. Participants were assigned to one of the two study conditions to enhance smoking cessation: Motivational Interviewing (MI; 6 sessions of MI + 8 weeks of NRT) or Standard Care (Brief advice to quit+ 8 weeks of NRT). The primary outcome for the current analysis was adherence to NRT at end of treatment (8 weeks following randomization). Adherence was defined as a total score of zero on a modified Morisky adherence scale). Demographic and baseline psychosocial, tobacco-related, and substance abuse measures were compared between those who did and did not adhere to NRT.

resultsAfter adjusting for confounders, smokers who were depressed at baseline (OR=0.58, 95% CI, 0.38-0.87, p=0.01), had lower confidence to quit (OR=1.10, 95% CI, 1.01-1.19, p=0.04), were less motivated to adhere (OR=1.04, 95% CI, 1.00-1.07, p=0.04), and were less likely to be adherent to NRT. Further, age of initial smoking was positively associated with adherence status (OR= 0.83, 95% CI, 0.69-0.99, p=0.04).

conclusionThese results suggest that smoking cessation programs conducted in this population may target increased adherence to NRT by addressing both depression and motivation to quit.

trial registrationclinicaltrials.gov: NCT00786149.

Indexed as

AdherenceHomeless populationsNicotine replacement therapyPatchRandomized controlled trialsSmoking cessation

Identifiers

PMID28580456
PMCPMC5453676

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.