Evidence map›Paper›PMID 28580440›Full record

ArticleScience immunology2016

Exploiting a host-commensal interaction to promote intestinal barrier function and enteric pathogen tolerance.

Virginia A Pedicord, Ainsley A K Lockhart, Kavita J Rangan, Jeffrey W Craig, Jakob Loschko, Aneta Rogoz, Howard C Hang, Daniel Mucida

Open access · greenAbstract read
In one paragraph

Article in Science immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 100 citations in OpenAlex.

  1. Article
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  4. Observational
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  9. Frontiers in microbiology · 2026
    Article
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5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Virginia A PedicordLaboratory of Mucosal Immunology, The Rockefeller University, New York, NY, USA.
Ainsley A K LockhartLaboratory of Mucosal Immunology, The Rockefeller University, New York, NY, USA.
Kavita J RanganLaboratory of Chemical Biology and Microbial Pathogenesis, The Rockefeller University, New York, NY, USA.
Jeffrey W CraigDepartment of Pathology, Brigham & Women's Hospital, Boston, MA, USA.
Jakob LoschkoLaboratory of Molecular Immunology, The Rockefeller University, New York, NY, USA.
Aneta RogozLaboratory of Mucosal Immunology, The Rockefeller University, New York, NY, USA.
Howard C HangLaboratory of Chemical Biology and Microbial Pathogenesis, The Rockefeller University, New York, NY, USA.
Daniel MucidaLaboratory of Mucosal Immunology, The Rockefeller University, New York, NY, USA.
Brigham and Women's Hospital · USRockefeller University · US

Funding

Elucidation of Commensal Bacteria Mechanisms Required for Host ProtectionR01GM103593 · NIGMS · ROCKEFELLER UNIVERSITY · PI HANG, HOWARD C · 2013 to 2020
$2.8M
NIGMS NIH HHS R01 GM103593
6 · The paper itself

Abstract

Commensal intestinal bacteria can prevent pathogenic infection; however, limited knowledge of the mechanisms by which individual bacterial species contribute to pathogen resistance has restricted their potential for therapeutic application. Here, we examined how colonization of mice with a human commensal

Identifiers

PMID28580440
PMCPMC5453653
OpenAlexW2523298690

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.