Evidence map›Paper›PMID 28580396›Full record

ArticleBone reports2016

Combined aerobic and resistance training improves bone health of female cancer survivors.

Hawley C Almstedt, Silvie Grote, Joshua R Korte, Stephanie Perez Beaudion, Todd C Shoepe, Sarah Strand, Heather P Tarleton

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bone reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Relative Effects of Radiation-Induced Changes in Bone Mass, Structure, and Tissue Material on Vertebral Strength in a Rat Model.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2023
    Article
  7. Review
  8. Article
  9. Article
  10. Exercise and Physical Activity in Patients with Osteosarcoma and Survivors.Advances in experimental medicine and biology · 2020
    Review
  11. Prediction of Low and Very Low Bone Mineral Density Among Adult Survivors of Childhood Cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2019
    Article
  12. Review
  13. Article
  14. Bleeding frequency and characteristics among hematologic malignancy inpatient rehabilitation patients with severe thrombocytopenia.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018
    Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Hawley C AlmstedtDepartment of Health and Human Sciences, Loyola Marymount University, Los Angeles, CA, USA.
Silvie GroteDepartment of Health and Human Sciences, Loyola Marymount University, Los Angeles, CA, USA.
Joshua R KorteDepartment of Health and Human Sciences, Loyola Marymount University, Los Angeles, CA, USA.
Stephanie Perez BeaudionDepartment of Health and Human Sciences, Loyola Marymount University, Los Angeles, CA, USA.
Todd C ShoepeDepartment of Health and Human Sciences, Loyola Marymount University, Los Angeles, CA, USA.
Sarah StrandDepartment of Health and Human Sciences, Loyola Marymount University, Los Angeles, CA, USA.
Heather P TarletonDepartment of Health and Human Sciences, Loyola Marymount University, Los Angeles, CA, USA.
Loyola Marymount University · USLoma Linda University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCancer pathogenesis and resulting treatment may lead to bone loss and poor skeletal health in survivorship. The purpose of this investigation was to evaluate the influence of 26 weeks of combined aerobic and resistance-training (CART) exercise on bone mineral density (BMD) in a multi-racial sample of female cancer survivors.

methodsTwenty-six female cancer survivors volunteered to undergo CART for 1 h/day, 3 days/week, for 26 weeks. The Improving Physical Activity After Cancer Treatment (IMPAACT) Program involves supervised group exercise sessions including 20 min of cardiorespiratory training, 25 min of circuit-style resistance-training, and 15 min of abdominal exercises and stretching. BMD at the spine, hip, and whole body was assessed using dual-energy X-ray absorptiometry (DXA) before and after the intervention. Serum markers of bone metabolism (procollagen-type I N-terminal propeptide, P1NP, and C-terminal telopeptides, CTX) were measured at baseline, 13 weeks, and at study completion.

resultsEighteen participants, with the average age of 63.0 ± 10.3 years, completed the program. Mean duration since completion of cancer treatment was 6.2 ± 10.6 years. Paired

conclusionsWe report significant improvements in BMD at the spine, hip, and whole body for female cancer survivors who completed 26 weeks of CART. This investigation demonstrates the possible effectiveness of CART at improving bone health and reducing risk of osteoporosis for women who have completed cancer treatment. The IMPAACT Program appears to be a safe and feasible way for women to improve health after cancer treatment.

Indexed as

BMD, bone mineral densityBone mineral densityBone turnover markersBTM, bone turnover markerCancer-induced bone lossCART, combined aerobic and resistance trainingCTX, C-terminal telopeptidesDXA, dual-energy X-ray absorptiometryFFQ, food frequency questionnaireIMPAACT, improving physical activity after cancer treatmentNTX, N-telopeptide cross-linked collagen type IOncologyOsteoporosisP1NP, procollagen-type I N-terminal propeptides

Identifiers

PMID28580396
PMCPMC5440970
OpenAlexW2521050935

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.