Evidence map›Paper›PMID 28580316›Full record

ArticleInternational journal of scientific and engineering research2017

Interactome Mapping Guided by Tissue-Specific Phosphorylation in Age-Related Macular Degeneration.

Srinivas R Sripathi, Weilue He, Cameron L Prigge, O'Donnell Sylvester, Ji-Yeon Um, Folami L Powell, Musa Neksumi, Paul S Bernstein, Dong-Won Choo, Manuela Bartoli and 2 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of scientific and engineering research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Mitochondrial quality control in AMD: does mitophagy play a pivotal role?Cellular and molecular life sciences : CMLS · 2018
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Srinivas R SripathiDepartment of Biological Sciences, Michigan Technological University, Houghton, MI, USA.
Weilue HeDepartment of Biomedical Engineering, Michigan Technological University, Houghton, MI, USA.
Cameron L PriggeDepartment of Biological Sciences, Michigan Technological University, Houghton, MI, USA.
O'Donnell SylvesterDepartment of Petroleum Chemistry, American University of Nigeria, Yola, Ada-mawa, Nigeria.
Ji-Yeon UmDepartment of Biological Sciences, Michigan Technological University, Houghton, MI, USA.
Folami L PowellDepartment of Ophthalmology, Augusta University, Augusta, GA, USA.
Musa NeksumiDepartment of Chemistry, Modibbo Adama University of Science and Technology, Yola, Adamawa, Nigeria.
Paul S BernsteinDepartment of Ophthalmology and Visual Sciences, Moran Eye Center, University of Utah School of Medicine, Salt Lake City, UT, USA.
Dong-Won ChooDepartment of Bioinformatics, Korea Polytechnic University, Geonggi, Korea.
Manuela BartoliDepartment of Ophthalmology, Augusta University, Augusta, GA, USA.
Diana R GutsaevaDepartment of Ophthalmology, Augusta University, Augusta, GA, USA.
Wan Jin JahngDepartment of Petroleum Chemistry, American University of Nigeria, Yola, Ada-mawa, Nigeria.
Augusta University · USMichigan Technological University · USSeoul National University of Science and Technology · KRUniversity of Utah · US

Funding

University of Utah, Core Vision Research GrantP30EY014800 · NEI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Bryan William Jones · 2005 to 2026
$14.6M
Vision Research Training Grant at the University of UtahT32EY024234 · NEI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI DAVID KRIZAJ, Monica L Vetter · 2014 to 2026
$2.3M
Depletion of iNKT Cells in the Treatment of Hypoxic Crises in Sickle Cell MiceR43HL123127 · NHLBI · NKT THERAPEUTICS, INC. · PI GUTSAEVA, DIANA R, SCHAUB, ROBERT · 2014 to 2014
$150k
NEI NIH HHS P30 EY014800NEI NIH HHS T32 EY024234NHLBI NIH HHS R43 HL123127
6 · The paper itself

Abstract

The current study aims to determine the molecular mechanisms of age-related macular degeneration (AMD) using the phosphorylation network. Specifically, we examined novel biomarkers for oxidative stress by protein interaction mapping using

Indexed as

AMDmitochondriaoxidative stressprotein interactomeproteomicsretinal pigment epithelium

Identifiers

PMID28580316
PMCPMC5450497
OpenAlexW2604230428

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.