ArticleNeuroImage. Clinical2017
Non-invasive, multimodal analysis of cortical activity, blood volume and neurovascular coupling in infantile spasms using EEG-fNIRS monitoring.
Article in NeuroImage. Clinical, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Cortical Region Reporting Patterns in Neurodevelopmental Disorders: A Systematic Review of fNIRS Studies.Biosensors · 2026Pooled it
- Strategic Integration: A Cross-Disciplinary Review of the fNIRS-EEG Dual-Modality Imaging System for Delivering Multimodal Neuroimaging to Applications.Brain sciences · 2024Review
- Longitudinal fNIRS and EEG metrics of habituation and novelty detection are correlated in 1-18-month-old infants.NeuroImage · 2023Article
- Functional near-infrared spectroscopy in pediatric clinical research: Different pathophysiologies and promising clinical applications.Neurophotonics · 2023Article
- Preictal neuronal and vascular activity precedes the onset of childhood absence seizure: direct current potential shifts and their correlation with hemodynamic activity.Neurophotonics · 2023Article
- The Effect of Electroencephalography Abnormalities on Cerebral Autoregulation in Sedated Ventilated Children.Pediatric reports · 2022Article
- Broadband-NIRS System Identifies Epileptic Focus in a Child with Focal Cortical Dysplasia-A Case Study.Metabolites · 2022Article
- Study Protocol of tDCS Based Pain Modulation in Head and Neck Cancer Patients Under Chemoradiation Therapy Condition: An fNIRS-EEG Study.Frontiers in molecular neuroscience · 2022Article
- Dynamics of cortical oxygenation during immediate adaptation to extrauterine life.Scientific reports · 2021Article
- Research progress of functional near-infrared spectroscopy in patients with psychiatric disorders.Forensic sciences research · 2021Review
- What Triggers the Interictal Epileptic Spike? A Multimodal Multiscale Analysis of the Dynamic of Synaptic and Non-synaptic Neuronal and Vascular Compartments Using Electrical and Optical Measurements.Frontiers in neurology · 2021Article
- Neurovascular coupling in the developing neonatal brain at rest.Human brain mapping · 2020Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although infantile spasms can be caused by a variety of etiologies, the clinical features are stereotypical. The neuronal and vascular mechanisms that contribute to the emergence of infantile spasms are not well understood. We performed a multimodal study by simultaneously recording electroencephalogram and functional Near-infrared spectroscopy in an intentionally heterogeneous population of six children with spasms in clusters. Regardless of the etiology, spasms were accompanied by two phases of hemodynamic changes; an initial change in the cerebral blood volume (simultaneously with each spasm) followed by a neurovascular coupling in all children except for the one with a large porencephalic cyst. Changes in cerebral blood volume, like the neurovascular coupling, occurred over frontal areas in all patients regardless of any brain damage suggesting a diffuse hemodynamic cortical response. The simultaneous motor activation and changes in cerebral blood volume might result from the involvement of the brainstem. The inconstant neurovascular coupling phase suggests a diffuse activation of the brain likely resulting too from the brainstem involvement that might trigger diffuse changes in cortical excitability.
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