Evidence map›Paper›PMID 28579957›Full record

ReviewFrontiers in pharmacology2017

The Epigenomics of Embryonic Pathway Signaling in Colorectal Cancer.

Curt Balch, Jayaram B Ramapuram, Amit K Tiwari

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Curt BalchDepartment of Pharmacology and Experimental Therapeutics, School of Pharmacy, University of Toledo, ToledoOH, USA.
Jayaram B RamapuramDepartment of Drug Discovery and Development, Auburn University, AuburnAL, USA.
Amit K TiwariDepartment of Pharmacology and Experimental Therapeutics, School of Pharmacy, University of Toledo, ToledoOH, USA.
University of Toledo · USAuburn University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) is the second-leading cause of cancer death in developed countries. While early detection (e.g., colonoscopy) generally yields excellent outcomes, metastatic and drug-resistant disease is uniformly fatal, and non-compliance for screening remains over 25%. Familial CRCs (10% of total cases) primarily include mutations in the gene

Indexed as

colorectal cancerembryonic signaling pathwaysepigenomicsepithelial-to-mesenchymal transitiontumor progression

Identifiers

PMID28579957
PMCPMC5437112
OpenAlexW2616305928

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.