Evidence map›Paper›PMID 28579779›Full record

ReviewInternational journal of nanomedicine2017

Antibacterial properties and toxicity from metallic nanomaterials.

Gina V Vimbela, Sang M Ngo, Carolyn Fraze, Lei Yang, David A Stout

Erratum issuedAbstract readReview
In one paragraph

Review in International journal of nanomedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 188 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
188citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

188 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review

128 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Gina V VimbelaDepartment of Chemical Engineering.
Sang M NgoDepartment of Electrical Engineering, California State University, Long Beach, CA.
Carolyn FrazeBrigham Young University Idaho, Rexburg, ID, USA.
Lei YangDepartment of Orthopaedics, Orthopaedic Institute, The First Affiliated Hospital.
David A StoutInternational Research Center for Translational Orthopaedics (IRCTO), Soochow University, Suzhou, Jiangsu, People's Republic of China.

Funding

CSULB Building Biomedical Research Program: Overall ComponentUL1GM118979 · NIGMS · CALIFORNIA STATE UNIVERSITY LONG BEACH · PI CHUN, CHI-AH, DILLON, JESSE · 2015 to 2023
$20.7M
National Research Mentoring Network for a Diverse Biomedical WorkforceU54GM119023 · NIGMS · BOSTON COLLEGE · PI OFILI, ELIZABETH O., OKUYEMI, KOLAWOLE S · 2015 to 2018
$15.3M
CSULB Building Biomedical Research Program: Student Training CoreTL4GM118980 · NIGMS · CALIFORNIA STATE UNIVERSITY LONG BEACH · PI CHUN, CHI-AH, DILLON, JESSE · 2015 to 2023
$12.3M
CSULB Building Biomedical Research Program: Research Enrichment CoreRL5GM118978 · NIGMS · CALIFORNIA STATE UNIVERSITY LONG BEACH · PI CHUN, CHI-AH, DILLON, JESSE · 2015 to 2023
$7.3M
NIGMS NIH HHS RL5 GM118978NIGMS NIH HHS TL4 GM118980NIGMS NIH HHS U54 GM119023NIGMS NIH HHS UL1 GM118979
6 · The paper itself

Abstract

The era of antibiotic resistance is a cause of increasing concern as bacteria continue to develop adaptive countermeasures against current antibiotics at an alarming rate. In recent years, studies have reported nanoparticles as a promising alternative to antibacterial reagents because of their exhibited antibacterial activity in several biomedical applications, including drug and gene delivery, tissue engineering, and imaging. Moreover, nanomaterial research has led to reports of a possible relationship between the morphological characteristics of a nanomaterial and the magnitude of its delivered toxicity. However, conventional synthesis of nanoparticles requires harsh chemicals and costly energy consumption. Additionally, the exact relationship between toxicity and morphology of nanomaterials has not been well established. Here, we review the recent advancements in synthesis techniques for silver, gold, copper, titanium, zinc oxide, and magnesium oxide nanomaterials and composites, with a focus on the toxicity exhibited by nanomaterials of multidimensions. This article highlights the benefits of selecting each material or metal-based composite for certain applications while also addressing possible setbacks and the toxic effects of the nanomaterials on the environment.

Indexed as

Anti-Bacterial AgentsMetal NanoparticlesAnimalsContrast MediaCopperDrug LiberationGenetic TherapyGoldHumansMagnesiumSilverTissue EngineeringTitaniumZincAnti-Bacterial AgentsContrast MediaCopperGoldMagnesiumSilverTitaniumZincantibacterial reagentsantibiotic resistancedrug deliverymetalsnanomaterialsnanoscalenanostructuresynthesistoxicity

Identifiers

PMID28579779
PMCPMC5449158

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.