ArticleInternational journal of chronic obstructive pulmonary disease2017
Clinical characteristics of COPD patients with tidal expiratory flow limitation.
Article in International journal of chronic obstructive pulmonary disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07364188 (Bronchodilator Response in COPD and Asthma), which is not on this map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Bronchodilator Response in COPD and Asthma: Correlation Between Spirometry, IOS Indices, and Dyspnea Relief
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- GOLD Science Committee recommendations for the use of pre- and post-bronchodilator spirometry for the diagnosis of COPD.The European respiratory journal · 2025Guideline
- The TRIFLOW study: a randomised, cross-over study evaluating the effects of extrafine beclometasone/formoterol/glycopyrronium on gas trapping in COPD.Respiratory research · 2020Trial
- Small airway dysfunction: a shared, early, measurable, and potentially treatable trait across COPD, asthma, and fibrotic lung disease.Frontiers in medicine · 2026Review
- Peripheral airway function and disease burden in COPD.ERJ open research · 2025Article
- Respiratory oscillometry in individuals with fibrodysplasia ossificans progressiva.Orphanet journal of rare diseases · 2025Article
- Maximal Forced Inspiratory Flow Dynamics and Acute Exacerbation in Chronic Obstructive Pulmonary Disease Patients with Exacerbation History.Tuberculosis and respiratory diseases · 2025Article
- Adherence to Inhalation Therapy Among COPD Patients: A Cross-Sectional Study in a Tertiary Hospital in Quito, Ecuador.International journal of chronic obstructive pulmonary disease · 2025Article
- The effect of expiratory flow limitation on supine persistent hyperinflation in COPD: a prospective observational study.ERJ open research · 2024Article
- Expiratory flow limitation development index (ELDI): a novel method of assessing respiratory mechanics in COPD.Respiratory research · 2024Article
- Oscillometry-Defined Small Airway Dysfunction in Patients with Chronic Obstructive Pulmonary Disease.Tuberculosis and respiratory diseases · 2024Article
- Diagnostic Potential of Oscillometry: A Population-based Approach.American journal of respiratory and critical care medicine · 2024Article
- Ventilators, Settings, Autotitration Algorithms.Journal of clinical medicine · 2023Review
- Investigation of the Methodology of Specific Airway Resistance Measurements in COPD.International journal of chronic obstructive pulmonary disease · 2023Article
- Intra-subject variability in oscillometry correlates with acute rejection and CLAD post-lung transplant.Frontiers in medicine · 2023Article
- Differences in Pulmonary Function Improvement after Once-Daily LABA/LAMA Fixed-Dose Combinations in Patients with COPD.Journal of clinical medicine · 2022Article
- Expiratory flow limitation in a cohort of highly symptomatic COPD patients.ERJ open research · 2022Article
- The clinical utility of forced oscillation technique during hospitalisation in patients with exacerbation of COPD.ERJ open research · 2021Article
- Review
- Relationships Between Forced Oscillatory Impedance and 6-minute Walk Distance After Pulmonary Rehabilitation in COPD.International journal of chronic obstructive pulmonary disease · 2020Observational
- Dismantling airway disease with the use of new pulmonary function indices.European respiratory review : an official journal of the European Respiratory Society · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We have used impulse oscillometry to identify COPD patients with tidal expiratory flow limitation (EFL), which is a measurement related to small airway disease. We report that 37.4% of COPD patients had EFL; these patients had multiple clinical characteristics of more severe disease including lower forced expiratory volume in 1 second values, greater hyperinflation, reduced exercise performance, and increased small airway impairment. We highlight that EFL can be used to identify a subgroup of COPD patients with distinct characteristics associated with small airway disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.