ReviewClinical interventions in aging2017
Cognitive decline in normal aging and its prevention: a review on non-pharmacological lifestyle strategies.
Review in Clinical interventions in aging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06968299 (Effect of ExoBDNF Lactic Acid Bacteria Supplement on Cognitive Functions, Sleep and Psychological Outcomes), which is not on this map. Cited by 59 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of ExoBDNF Lactic Acid Bacteria Supplement on Cognitive Functions, Sleep and Psychological Outcomes: An Open-label Trial
Who cites it
59 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Harmonious ageing: a narrative review of music therapy in the biomedical literature.European geriatric medicine · 2025Pooled it
- Acquisition of musical skills and abilities in older adults-results of 12 months of music training.BMC geriatrics · 2024Trial
- The effects of six months Persicaria minor extract supplement among older adults with mild cognitive impairment: a double-blinded, randomized, and placebo-controlled trial.BMC complementary medicine and therapies · 2020Trial
- Cognitive enhancement of healthy older adults using hyperbaric oxygen: a randomized controlled trial.Aging · 2020Trial
- The interactive Physical and Cognitive Exercise System (iPACES™): effects of a 3-month in-home pilot clinical trial for mild cognitive impairment and caregivers.Clinical interventions in aging · 2018Trial
- Bridging pathologies: Mechanistic insights into the diabetes-Alzheimer's nexus.EXCLI journal · 2026Review
- ExoBDNF Probiotic Supplementation Enhances Cognition in Subjective Cognitive Decline.Medicina (Kaunas, Lithuania) · 2025Article
- The impact of lifestyle factors on trajectories of cognitive subtypes in the older adult population.Scientific reports · 2025Article
- ACTIVA-Senior: Study Design and Protocol for a Preliminary Multidomain Outdoor Intervention Promoting Healthy Aging and Mitigating Psycho-Physiological Decline.Healthcare (Basel, Switzerland) · 2025Article
- Evaluating the Effectiveness of Cognitive Interventions for Healthy and Mild Cognitive Impairment Adults: A Comprehensive Umbrella Meta-Analysis.Journal of aging research · 2025Review
- Second language learning in older adults modulates Stroop task performance and brain activation.Frontiers in aging neuroscience · 2024Article
- Caring for Individuals with Alzheimer's Disease: A Spotlight on Hispanic Caregivers.Journal of Alzheimer's disease reports · 2024Review
- A quasi-experimental mixed-method pilot study to check the efficacy of the "SOUND" active and passive music-based intervention on mental wellbeing and residual cognition of older people with dementia and dementia professionals' burnout: a research protocol.Frontiers in psychology · 2024Article
- Efficacy of Transcranial Direct Current Stimulation (tDCS) on Cognition, Anxiety, and Mobility in Community-Dwelling Older Individuals: A Controlled Clinical Trial.Brain sciences · 2023Article
- Impact of Using Smartphone While Walking or Standing: A Study Focused on Age and Cognition.Brain sciences · 2023Article
- The aging mind: A complex challenge for research and practice.Aging brain · 2023Review
- Predicting mild cognitive impairment among Chinese older adults: a longitudinal study based on long short-term memory networks and machine learning.Frontiers in aging neuroscience · 2023Article
- Longitudinal changes in grey matter and cognitive performance over four years of healthy aging.Neuroimage. Reports · 2022Article
- Normal pace walking is beneficial to young participants' executive abilities.BMC sports science, medicine & rehabilitation · 2022Article
- A Non-Randomized Combined Program of Walking and Low-Load Resistance Exercise Improves Cognitive Function and Cardiometabolic Risk Factors in Community-Dwelling Elderly Women.Healthcare (Basel, Switzerland) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of this study is to examine the effects of the selected non-pharmacological lifestyle activities on the delay of cognitive decline in normal aging. This was done by conducting a literature review in the four acknowledged databases Web of Science, Scopus, MEDLINE, and Springer, and consequently by evaluating the findings of the relevant studies. The findings show that physical activities, such as walking and aerobic exercises, music therapy, adherence to Mediterranean diet, or solving crosswords, seem to be very promising lifestyle intervention tools. The results indicate that non-pharmacological lifestyle intervention activities should be intense and possibly done simultaneously in order to be effective in the prevention of cognitive decline. In addition, more longitudinal randomized controlled trials are needed in order to discover the most effective types and the duration of these intervention activities in the prevention of cognitive decline, typical of aging population groups.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.