Evidence map›Paper›PMID 28579491›Full record

ArticleNeuroscience and biobehavioral reviews2017

Recommendation to reconsider examining cannabis subtypes together due to opposing effects on brain, cognition and behavior.

Kristine Rømer Thomsen, Mette Buhl Callesen, Sarah W Feldstein Ewing

Abstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuroscience and biobehavioral reviews, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  4. Observational
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  8. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Kristine Rømer ThomsenCentre for Alcohol and Drug Research, Department of Psychology and Behavioural Sciences, Aarhus University, Bartholins Allé 10, 8000 Aarhus C, Denmark. Electronic address: krt.crf@psy.au.dk.
Mette Buhl CallesenCentre for Alcohol and Drug Research, Department of Psychology and Behavioural Sciences, Aarhus University, Bartholins Allé 10, 8000 Aarhus C, Denmark.
Sarah W Feldstein EwingDepartment of Child and Adolescent Psychiatry, Oregon Health and Science University, Mail Code: DC7, 3181 SW Sam Jackson Park Rd, Portland, OR 97239-3098, USA.

Funding

fMRI and Treatment Response with Binge Drinking AdolescentsR01AA023658 · NIAAA · UNIVERSITY OF RHODE ISLAND · PI FELDSTEIN EWING, SARAH W. · 2015 to 2019
$1.7M
NIAAA NIH HHS R01 AA023658
6 · The paper itself

Abstract

Cannabis use represents a major public health issue throughout the globe. Yet, we still lack the most fundamental knowledge on long-term effects of cannabis on neural, cognitive, and behavioral function. Part of this stems from how cannabis has been measured historically. To this end, most empirical examinations of cannabis have consolidated all types of cannabis collectively. However, this approach obscures differences in how cannabinoids operate. In this commentary, we address the contrasting properties of tetrahydrocannabinol (THC) and cannabidiol (CBD) and their opposing effects on cognitive function. In addition, we address the increase in cannabis potency throughout the past two decades and how that impacts generalizability of early data to evaluations of contemporary public health. We underscore the urgent need for future research to disaggregate examination of THC from CBD, along with the importance of measuring cannabis potency to more effectively unravel its influence on cognitive function and other health issues.

Indexed as

CannabisSchizophreniaBrainCannabidiolCognitionDronabinolHumansCannabidiolDronabinolCannabidiolCannabisCognitionDelta-9-tetrahydrocannabinolLearningMemoryPotency

Identifiers

PMID28579491
PMCPMC6373765

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.