Evidence map›Paper›PMID 28579319›Full record

ReviewTrends in immunology2017

Immunological Functions of the Omentum.

Selene Meza-Perez, Troy D Randall

Open access · greenAbstract readReview
In one paragraph

Review in Trends in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 198 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
198citing papers in PubMed, 5 pooled it
20.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

198 citing papers in PubMed, 5 syntheses or guidelines pooled it, 321 citations in OpenAlex.

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138 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Selene Meza-PerezDepartment of Medicine, Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Troy D RandallDepartment of Medicine, Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Electronic address: randallt@uab.edu.
University of Alabama at Birmingham · US

Funding

XRAY CRYSTALLOGRAPHYP30CA013148 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Robert S Welner · 1985 to 2026
$165.9M
Virus-induced Cell Fate Decisions in Anti-Viral ImmunityU19AI109962 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LUND, FRANCES E. · 2014 to 2018
$11.6M
Unique Aspects of Respiratory ImmunityR01HL069409 · NHLBI · UNIVERSITY OF ROCHESTER · PI RANDALL, TROY D · 2001 to 2015
$5.3M
Role of microbiota in therapy to ovarian cancerR01CA216234 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI RANDALL, TROY D · 2017 to 2021
$2.1M
NCI NIH HHS P30 CA013148NCI NIH HHS R01 CA216234NHLBI NIH HHS R01 HL069409NIAID NIH HHS U19 AI109962
6 · The paper itself

Abstract

The omentum is a visceral adipose tissue with unique immune functions. Although it is primarily an adipose tissue, the omentum also contains lymphoid aggregates, called milky spots (MSs), that contribute to peritoneal immunity by collecting antigens, particulates, and pathogens from the peritoneal cavity and, depending on the stimuli, promoting a variety of immune responses, including inflammation, tolerance, or even fibrosis. Reciprocal interactions between cells in the MS and adipocytes regulate their immune and metabolic functions. Importantly, the omentum collects metastasizing tumor cells and supports tumor growth by immunological and metabolic mechanisms. Here we summarize our current knowledge about the development, organization, and function of the omentum in peritoneal immunity.

Indexed as

AdipocytesAdipose TissueAnimalsB-LymphocytesCell CommunicationCytokinesEpitheliumGene Expression RegulationHumansLymphoid TissueMacrophagesOmentumReceptors, CytokineSignal TransductionT-Lymphocytes, RegulatoryCytokinesReceptors, Cytokine

Identifiers

PMID28579319
PMCPMC5812451
OpenAlexW2620731633

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.