Evidence map›Paper›PMID 28579202›Full record

Observational studySurgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery2017

Use of prescribed opioids before and after bariatric surgery: prospective evidence from a U.S. multicenter cohort study.

Wendy C King, Jia-Yuh Chen, Steven H Belle, Anita P Courcoulas, Gregory F Dakin, David R Flum, Marcelo W Hinojosa, Melissa A Kalarchian, James E Mitchell, Walter J Pories and 5 more

Registry-linked trialOpen access · greenAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04073056 (Quadratus Lumborum II Block vs Conventional Therapy Alone For Laparoscopic Sleeve Gastrectomy), which is not on this map. Cited by 40 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 3 pooled it
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04073056 phase4completednot on this mapstarted 2018, after this paper: background citation

Quadratus Lumborum II Block vs Conventional Therapy Alone For Laparoscopic Sleeve Gastrectomy

TypeinterventionalSponsorIcahn School of Medicine at Mount SinaiRan2018 to 2021Enrolled41ConditionsMorbid Obesity, High BMIArmsBupivacaine
3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 3 syntheses or guidelines pooled it, 98 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 10 institutions in 1 country.

Wendy C KingDepartment of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania. Electronic address: kingw@edc.pitt.edu.
Jia-Yuh ChenDepartment of Biostatistics, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania.
Steven H BelleDepartment of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania.
Anita P CourcoulasDepartment of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
Gregory F DakinWeill Cornell Medical College, New York, New York.
David R FlumDepartment of Surgery, University of Washington, Seattle, Washington.
Marcelo W HinojosaDepartment of Surgery, University of Washington, Seattle, Washington.
Melissa A KalarchianDepartment of Psychiatry, University of Pittsburgh School of Medicine, and Duquesne University School of Nursing, Pittsburgh, Pennsylvania.
James E MitchellNeuropsychiatric Research Institute, Fargo, North Dakota.
Walter J PoriesDepartment of Surgery, Brody School of Medicine, East Carolina University, Greenville, North Carolina.
Konstantinos SpaniolasDepartment of Surgery, Brody School of Medicine, East Carolina University, Greenville, North Carolina.
Bruce M WolfeDepartment of Surgery, Oregon Health Sciences University, Portland, Oregon.
Susan Z YanovskiDivision of Digestive Diseases and Nutrition, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland.
Scott G EngelNeuropsychiatric Research Institute, Fargo, North Dakota.
Kristine J SteffenNeuropsychiatric Research Institute, Fargo, North Dakota; Department of Pharmaceutical Sciences, North Dakota State University, Fargo, North Dakota.
University of Pittsburgh · USEast Carolina University · USNeuropsychiatric Research Institute · USUniversity of Washington · USCornell University · USDuquesne University · USNational Institute of Diabetes and Digestive and Kidney Diseases · USNorth Dakota State University · USOregon Health & Science University · USUniversity of Pittsburgh Medical Center · US

Funding

Disparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2M
UNIVERSITY OF PITTSBURGH CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTE: BPCAUL1RR024153 · NCRR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2006 to 2011
$73.9M
CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR024996 · NCRR · WEILL MEDICAL COLL OF CORNELL UNIV · PI IMPERATO-MCGINLEY, JULIANNE L · 2007 to 2011
$49.6M
ZIPRASIDONE IN NORMAL HEPATIC FUNCTION SUBJECTS &IN HEPATIC DYSFUCTIN SUBJECTSM01RR000037 · NCRR · UNIVERSITY OF WASHINGTON · PI MCDONALD, RUTH C · 1985 to 2007
$33.8M
Continuation of the Longitudinal Assessment of Bariatric Surgery (LABS) - DCCU01DK066557 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BELLE, STEVEN H. · 2003 to 2015
$15.8M
BARIATRIC SURGERY CLINICAL RESEARCH CONSORTIUMU01DK066555 · NIDDK · UNIVERSITY OF CALIFORNIA DAVIS · PI WOLFE, BRUCE M · 2003 to 2013
$6.2M
Effect of Bariatric Surgery on Insulin Resistance &CVDU01DK066585 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI COURCOULAS, ANITA P · 2003 to 2013
$5.0M
Bariatric Surgery: Outcomes & Impact on PathophysiologyU01DK066667 · NIDDK · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI BERK, PAUL DAVID, POMP, ALFONS · 2003 to 2015
$4.7M
Longtitudinal Assessment of Bariatric Surgery (LABS)U01DK066568 · NIDDK · UNIVERSITY OF WASHINGTON · PI FLUM, DAVID R · 2003 to 2013
$4.3M
East Carolina University Bariatric Surgery Clinical CenterU01DK066526 · NIDDK · EAST CAROLINA UNIVERSITY · PI PORIES, WALTER JULIUS · 2003 to 2015
$4.0M
Longitudinal Assessment of Bariatric Surgery (LABS)U01DK066471 · NIDDK · SANFORD RESEARCH NORTH · PI MITCHELL, JAMES EDWARD · 2003 to 2015
$3.7M
NCATS NIH HHS UL1 TR002384NCRR NIH HHS M01 RR000037NCRR NIH HHS UL1 RR024153NCRR NIH HHS UL1 RR024996NIDDK NIH HHS U01 DK066471NIDDK NIH HHS U01 DK066526NIDDK NIH HHS U01 DK066555NIDDK NIH HHS U01 DK066557NIDDK NIH HHS U01 DK066568NIDDK NIH HHS U01 DK066585NIDDK NIH HHS U01 DK066667
6 · The paper itself

Abstract

backgroundLimited evidence suggests bariatric surgery may not reduce opioid analgesic use, despite improvements in pain.

objectiveTo determine if use of prescribed opioid analgesics changes in the short and long term after bariatric surgery and to identify factors associated with continued and postsurgery initiated use.

settingTen U.S. hospitals.

methodsThe Longitudinal Assessment of Bariatric Surgery-2 is an observational cohort study. Assessments were conducted presurgery, 6 months postsurgery, and annually postsurgery for up to 7 years until January 2015. Opioid use was defined as self-reported daily, weekly, or "as needed" use of a prescribed medication classified as an opioid analgesic.

resultsOf 2258 participants with baseline data, 2218 completed follow-up assessment(s) (78.7% were female, median body mass index: 46; 70.6% underwent Roux-en-Y gastric bypass). Prevalence of opioid use decreased after surgery from 14.7% (95% CI: 13.3-16.2) at baseline to 12.9% (95% CI: 11.5-14.4) at month 6 but then increased to 20.3%, above baseline levels, as time progressed (95% CI: 18.2-22.5) at year 7. Among participants without baseline opioid use (n = 1892), opioid use prevalence increased from 5.8% (95% CI: 4.7-6.9) at month 6 to 14.2% (95% CI: 12.2-16.3) at year 7. Public versus private health insurance, more pain presurgery, undergoing subsequent surgeries, worsening or less improvement in pain, and starting or continuing nonopioid analgesics postsurgery were significantly associated with higher risk of postsurgery initiated opioid use.

conclusionAfter bariatric surgery, prevalence of prescribed opioid analgesic use initially decreased but then increased to surpass baseline prevalence, suggesting the need for alternative methods of pain management in this population.

Indexed as

AdultAnalgesics, OpioidBariatric SurgeryCohort StudiesFemaleGastric BypassGastroplastyHumansMaleMiddle AgedObesity, MorbidPostoperative CarePostoperative PainPreoperative CareAnalgesics, OpioidAnalgesiaBariatric surgeryLaparoscopic adjustable gastric bandMedicationNarcoticOpioidPainRoux-en-Y gastric bypassSevere obesity

Identifiers

PMID28579202
PMCPMC5568488
OpenAlexW2604644189

What OpenQuestion holds

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LicenceTDM
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.