Evidence map›Paper›PMID 28578877›Full record

ArticleHearing research2017

Progression of changes in the sensorial elements of the cochlear and peripheral vestibular systems: The otitis media continuum.

Rafael da Costa Monsanto, Patricia Schachern, Michael M Paparella, Sebahattin Cureoglu, Norma de Oliveira Penido

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Hearing research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
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  4. Review
  5. Article
  6. Presentation of dizziness in individuals with chronic otitis media: data from the multinational collaborative COMQ-12 study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022
    Article
  7. Quantitative assessment of cochlear and vestibular ganglion neurons in temporal bones with chronic otitis media.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021
    Article
  8. Article
  9. Histopathology of Inner Ear Malformations: Potential Pitfalls for Cochlear Implantation.Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2019
    Article
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Rafael da Costa MonsantoDepartment of Otolaryngology, University of Minnesota, 2001 6th St. SE, Lions Research Building, Room 210, Otopathology Laboratory, Minneapolis, MN 55455, USA; Department of Otorhinolaryngology Head and Neck Surgery, Universidade Federal de São Paulo (UNIFESP), Escola Paulista de Medicina, Rua dos Otonis, 700 - Piso Superior - Vila Clementino, São Paulo, SP 04025 002, Brazil.
Patricia SchachernDepartment of Otolaryngology, University of Minnesota, 2001 6th St. SE, Lions Research Building, Room 210, Otopathology Laboratory, Minneapolis, MN 55455, USA.
Michael M PaparellaDepartment of Otolaryngology, University of Minnesota, 2001 6th St. SE, Lions Research Building, Room 210, Otopathology Laboratory, Minneapolis, MN 55455, USA.
Sebahattin CureogluDepartment of Otolaryngology, University of Minnesota, 2001 6th St. SE, Lions Research Building, Room 210, Otopathology Laboratory, Minneapolis, MN 55455, USA. Electronic address: cureo003@umn.edu.
Norma de Oliveira PenidoDepartment of Otorhinolaryngology Head and Neck Surgery, Universidade Federal de São Paulo (UNIFESP), Escola Paulista de Medicina, Rua dos Otonis, 700 - Piso Superior - Vila Clementino, São Paulo, SP 04025 002, Brazil.
University of Minnesota · USUniversidade Federal de São Paulo · BR

Funding

Pathology and pathogenesis of otitis media syndromic ear and Meniere's diseaseU24DC011968 · NIDCD · UNIVERSITY OF MINNESOTA · PI CUREOGLU, SEBAHATTIN · 2011 to 2015
$2.2M
NIDCD NIH HHS U24 DC011968
6 · The paper itself

Abstract

Our study aimed to evaluate pathologic changes in the cochlear (inner and outer hair cells and stria vascularis) and vestibular (vestibular hair cells, dark, and transitional cells) sensorial elements in temporal bones from donors who had otitis media. We studied 40 temporal bones from such donors, which were categorized in serous otitis media (SOM), serous-purulent otitis media (SPOM), mucoid/mucoid-purulent otitis media (MOM/MPOM), and chronic otitis media (COM); control group comprised 10 nondiseased temporal bones. We found significant loss of inner and outer cochlear hair cells in the basal turn of the SPOM, MOM/MPOM and COM groups; significant loss of vestibular hair cells was observed in the MOM/MPOM and COM groups. All otitis media groups had smaller mean area of the stria vascularis in the basal turn of the cochlea when compared to controls. In conclusion, our study demonstrated more severe pathologic changes in the later stages of the continuum of otitis media (MOM/MPOM and COM). Those changes seem to progress from the basal turn of the cochlea (stria vascularis, then inner and outer hair cells) to the middle turn of the cochlea and to the saccule and utricle in the MOM/MPOM and COM stages.

Indexed as

AdolescentAdultAgedAged, 80 and overCase-Control StudiesCochleaFemaleHair Cells, Auditory, InnerHair Cells, Auditory, OuterHair Cells, VestibularHumansMaleMiddle AgedOtitis Media, SuppurativeOtitis Media with EffusionTemporal BoneCochlear hair cellsCochlear pathologyOtitis mediaStria vascularisVestibular hair cellsVestibular pathology

Identifiers

PMID28578877
PMCPMC6557455
OpenAlexW2618783461

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.