Evidence map›Paper›PMID 28578748›Full record

ArticleDisaster medicine and public health preparedness2018

Epidemiological Effectiveness and Cost of a Fungal Meningitis Outbreak Response in New River Valley, Virginia: Local Health Department and Clinical Perspectives.

Nargesalsadat Dorratoltaj, Margaret L O'Dell, Paige Bordwine, Thomas M Kerkering, Kerry J Redican, Kaja M Abbas

Abstract read
In one paragraph

Article in Disaster medicine and public health preparedness, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Characteristics and Distribution of Fungal Meningitis: A Systematic Review.Infectious diseases & clinical microbiology · 2025
    Article
  2. Review
  3. Recognition of fungal priority pathogens: What next?PLoS neglected tropical diseases · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nargesalsadat Dorratoltaj1Department of Population Health Sciences,Virginia Tech,Blacksburg,Virginia.
Margaret L O'Dell2New River Health District,Virginia Department of Health,Christiansburg,Virginia.
Paige Bordwine2New River Health District,Virginia Department of Health,Christiansburg,Virginia.
Thomas M Kerkering3Division of Infectious Diseases,Virginia Tech Carilion School of Medicine,Roanoke,Virginia.
Kerry J Redican1Department of Population Health Sciences,Virginia Tech,Blacksburg,Virginia.
Kaja M Abbas1Department of Population Health Sciences,Virginia Tech,Blacksburg,Virginia.

Funding

Systems Analysis of Social Pathways of Epidemics to Reduce Health DisparitiesR01GM109718 · NIGMS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI MARATHE, ACHLA, VULLIKANTI, ANIL · 2014 to 2022
$3.6M
NIGMS NIH HHS R01 GM109718
6 · The paper itself

Abstract

objectiveWe evaluated the effectiveness and cost of a fungal meningitis outbreak response in the New River Valley of Virginia during 2012-2013 from the perspective of the local public health department and clinical facilities. The fungal meningitis outbreak affected 23 states in the United States with 751 cases and 64 deaths in 20 states; there were 56 cases and 5 deaths in Virginia.

methodsWe conducted a partial economic evaluation of the fungal meningitis outbreak response in New River Valley. We collected costs associated with the local health department and clinical facilities in the outbreak response and estimated the epidemiological effectiveness by using disability-adjusted life years (DALYs) averted.

resultsWe estimated the epidemiological effectiveness of this outbreak response to be 153 DALYs averted among the patients, and the costs incurred by the local health department and clinical facilities to be $30,413 and $39,580, respectively.

conclusionsWe estimated the incremental cost-effectiveness ratio of $198 per DALY averted and $258 per DALY averted from the local health department and clinical perspectives, respectively, thereby assisting in impact evaluation of the outbreak response by the local health department and clinical facilities. (Disaster Med Public Health Preparedness. 2018;12:38-46).

Indexed as

Costs and Cost AnalysisDecision Support TechniquesDisaster MedicineDisease OutbreaksDrug ContaminationGlucocorticoidsHumansInjections, EpiduralLocal GovernmentMeningitis, FungalMethylprednisolonePublic HealthQuality-Adjusted Life YearsVirginiaGlucocorticoidsMethylprednisoloneclinicalcost-effectiveness analysisfungal meningitis outbreaklocal health departmentNew River ValleyVirginia

Identifiers

PMID28578748
PMCPMC5716923

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.