Trial reportCritical care (London, England)2017
Effects of neurally adjusted ventilatory assist on air distribution and dead space in patients with acute exacerbation of chronic obstructive pulmonary disease.
Trial report in Critical care (London, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02289573 (Effects of NAVA and PSV to AECOPD Patients' Air Distribution and Dead Space), which is not on this map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of NAVA and PSV to AECOPD Patients' Air Distribution and Dead Space
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Diagnostic and clinical values of non-cardiac ultrasound in COPD: A systematic review.BMJ open respiratory research · 2020Pooled it
- Neurally adjusted ventilatory assist vs pressure support ventilation: short-term effects on shunt and dead space after cardiac surgery.Scientific reports · 2025Trial
- Effects of external diaphragmatic pacing with neurally adjusted ventilatory assist on diaphragm function in AECOPD patients.Scientific reports · 2025Trial
- Trial
- Clinical applications of electrical impedance tomography in pediatric subjects.Pediatric research · 2026Review
- Application of neurally adjusted ventilatory assist (NAVA): a narrative review.Journal of thoracic disease · 2025Review
- Expert opinion document: "Electrical impedance tomography: applications from the intensive care unit and beyond".Journal of anesthesia, analgesia and critical care · 2022Review
- System introduction and evaluation of the first Chinese chest EIT device for ICU applications.Scientific reports · 2021Observational
- Regional ventilation distribution in healthy lungs: can reference values be established for electrical impedance tomography parameters?Annals of translational medicine · 2021Article
- First Attempt at Using Electrical Impedance Tomography to Predict High Flow Nasal Cannula Therapy Outcomes at an Early Phase.Frontiers in medicine · 2021Article
- A narrative review of electrical impedance tomography in lung diseases with flow limitation and hyperinflation: methodologies and applications.Annals of translational medicine · 2020Review
- A Review of Electrical Impedance Tomography in Lung Applications: Theory and Algorithms for Absolute Images.Annual reviews in control · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNeurally adjusted ventilatory assist (NAVA) could improve patient-ventilator interaction; its effects on ventilation distribution and dead space are still unknown. The aim of this study was to evaluate the effects of varying levels of assist during NAVA and pressure support ventilation (PSV) on ventilation distribution and dead space in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD).
methodsFifteen mechanically ventilated patients with AECOPD were included in the study. The initial PSV levels were set to 10 cmH
resultsThe trigger and cycle delays were lower during NAVA than during PSV. The work of trigger was significantly lower during NAVA compared to PSV. The diaphragm activities based on ultrasonography were higher during NAVA compared to the same support level during PSV. The ventilation distribution in ROI4 increased significantly (P < 0.05) during NAVA compared to PSV (except for a support level of 50%). Similar results were found in ROI3 + 4. NAVA reduced dead space fraction compared to the corresponding support level of PSV.
conclusionsNAVA was superior to PSV in AECOPD for increasing ventilation distribution in ROI4 and reducing dead space.
trial registrationClinicaltrials.gov, NCT02289573 . Registered on 12 November 2014.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.