Observational studyBreast cancer research and treatment2017
Family history and risk of breast cancer: an analysis accounting for family structure.
Observational study in Breast cancer research and treatment, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 136 papers, 9 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
136 citing papers in PubMed, 9 syntheses or guidelines pooled it, 302 citations in OpenAlex.
- Socioeconomic factors affecting breast and cervical cancer screening compliance in Asian National Cancer Centers Alliance countries: a systematic review.Epidemiology and health · 2025Pooled it
- Breast cancer and its determinants in Ethiopia: a systematic review and meta-analysis.BMJ open · 2024Pooled it
- Breast cancer risk factors in Iranian women: a systematic review and meta-analysis of matched case-control studies.European journal of medical research · 2022Pooled it
- Mammographic breast density and the risk of breast cancer: A systematic review and meta-analysis.Breast (Edinburgh, Scotland) · 2022Pooled it
- Risk factors for breast cancer in women: an update review.Medical oncology (Northwood, London, England) · 2022Pooled it
- Association between fertility treatments and breast cancer risk in women with a family history or BRCA mutations: a systematic review and meta-analysis.Frontiers in endocrinology · 2022Pooled it
- Breast Cancer Risk From Modifiable and Non-Modifiable Risk Factors among Palestinian Women: A Systematic Review and Meta-Analysis.Asian Pacific journal of cancer prevention : APJCP · 2021Pooled it
- Pooled it
- Prevalence of BRCA mutations among hereditary breast and/or ovarian cancer patients in Arab countries: systematic review and meta-analysis.BMC cancer · 2019Pooled it
- Mothers' experiences of having a daughter with breast cancer in Chinese families: A qualitative study.Asia-Pacific journal of oncology nursing · 2026Article
- Daucosterol linoleate from sweet potato inhibits breast cancer metastasis via SCD1 downregulation and suppression of epithelial-mesenchymal transition.Human cell · 2026Article
- The Effect of Culture-Based Breast Health Education Program on Breast Self-Examination Practice Among High-Risk Women: Randomized Controlled Trial.Asian/Pacific Island nursing journal · 2026Article
- Pathological Complete Response After Neoadjuvant Chemotherapy in Breast Cancer: A Literature Overview.Cancers · 2026Review
- Comparison of breast cancer awareness and attitudes toward screenings in women with and without a family history.BMC cancer · 2026Article
- The Future of Breast Cancer Treatment: From Conventional Wisdom to Nanotechnology-Enabled Precision.International journal of molecular sciences · 2026Review
- Frequency of Founder Mutations inCancers · 2026Review
- Can I Do Better Than AI: A Comparative Analysis of a Medical Student Essay Created With and Without Generative AI.Cureus · 2026Article
- A pro-carcinogenic oral microbe internalized by breast cancer cells promotes mammary tumorigenesis.Cell communication and signaling : CCS · 2026Article
- Modifiable and Nonmodifiable Risk Factors for Breast Cancer: A Comprehensive Scoping Review.International journal of breast cancer · 2026Review
- Breast Cancer During Pregnancy and Lactation: A Five-Year Retrospective Study in Sudan.Cureus · 2026Article
76 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeFamily history is an important risk factor for breast cancer incidence, but the parameters conventionally used to categorize it are based solely on numbers and/or ages of breast cancer cases in the family and take no account of the size and age-structure of the woman's family.
methodsUsing data from the Generations Study, a cohort of over 113,000 women from the general UK population, we analyzed breast cancer risk in relation to first-degree family history using a family history score (FHS) that takes account of the expected number of family cases based on the family's age-structure and national cancer incidence rates.
resultsBreast cancer risk increased significantly (P
conclusionsA family history score based on expected as well as observed breast cancers in a family can give greater risk discrimination on breast cancer incidence than conventional parameters based solely on cases in affected relatives. Our modeling suggests that a yet stronger predictor of risk might be a combination of this score and age at diagnosis in relatives.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.