Evidence map›Paper›PMID 28578486›Full record

ArticleChinese journal of integrative medicine2018

Angelica tenuissima Nakai Ameliorates Cognitive Impairment and Promotes Neurogenesis in Mouse Model of Alzheimer's Disease.

Minji Choi, Younghyurk Lee, Seung-Hun Cho

Abstract read
PubMed Publisher
In one paragraph

Article in Chinese journal of integrative medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Expression patterns of AEG-1 in the normal brain.Brain structure & function · 2023
    Article
  6. Plants (Basel, Switzerland) · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Experimental biology and medicine (Maywood, N.J.) · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Minji ChoiDepartment of Psychiatry, Hospital of Korean Medicine, Kyung Hee University Medical Center, Seoul, 130-872, South Korea.
Younghyurk LeeDepartment of Psychiatry, Hospital of Korean Medicine, Kyung Hee University Medical Center, Seoul, 130-872, South Korea.
Seung-Hun ChoDepartment of Psychiatry, Hospital of Korean Medicine, Kyung Hee University Medical Center, Seoul, 130-872, South Korea. chosh@khmc.or.kr.
Kyung Hee University Medical Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo research Angelica tenuissima Nakai (ATN) for use in novel Alzheimer's disease (AD) therapeutics.

methodsThe effect of a 30% ethanol extract of ATN (KH032) on AD-like cognitive impairment and neuropathological and neuroinflammatory changes induced by bilateral intracerebroventricular injections of β-amyloid (Aβ) peptide (Aβ

resultsKH032 treatment ameliorated cognitive impairments, reduced the overexpression of Aβ

conclusionsKH032 attenuated cognitive defificits in the Aβ

Indexed as

NeurogenesisAlzheimer DiseaseAmyloid beta-PeptidesAngelicaAnimalsBrainBrain-Derived Neurotrophic FactorCognitive DysfunctionCyclic AMP Response Element-Binding ProteinDisease Models, AnimalMaleMaze LearningMemory, Short-TermMice, Inbred C57BLNeurogliaNeuronsAmyloid beta-PeptidesBrain-Derived Neurotrophic FactorCyclic AMP Response Element-Binding ProteinNeuroprotective AgentsPlant ExtractsAlzheimer’s diseaseAngelica tenuissima Nakaibeta amyloidcognitive impairmentneurogenesis

Identifiers

PMID28578486
OpenAlexW2620960887

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.