ArticleThe Journal of allergy and clinical immunology2017
Prevalence of food allergies and intolerances documented in electronic health records.
Article in The Journal of allergy and clinical immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 2 of them syntheses that pooled it.
What it found
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Who cites it
49 citing papers in PubMed, 2 syntheses or guidelines pooled it, 118 citations in OpenAlex.
- Effects of Sex and Gender in Immediate β-Lactam Antibiotic Allergy: A Systematic Review and Meta-Analysis.The journal of allergy and clinical immunology. In practice · 2025Pooled it
- Multi-Perspective Observation on the Prevalence of Food Allergy in the General Chinese Population: A Meta-Analysis.Nutrients · 2022Pooled it
- Potential Use of Hazelnut Beverage in Water Kefir Fermentation: Effects of Sugar Addition on Physicochemical, Microbiological, Rheological, Bioactive, Volatile, and Allergenic Properties.Journal of food science · 2026Article
- Mast cell proteases and their significance in physiology, pathology, and therapeutic approaches.Pharmacological reviews · 2026Review
- Peanut Genotypes with Reduced Content of Immunogenic Proteins by Breeding, Biotechnology, and Management: Prospects and Challenges.Plants (Basel, Switzerland) · 2025Article
- Article
- Mast cell-derived IL-10 protects intestinal barrier integrity during malaria in mice and regulates parasite transmission toInfection and immunity · 2024Article
- Food Safety-Transcriptomics and Proteomics.International journal of molecular sciences · 2023Article
- Myths and Facts about Food Intolerance: A Narrative Review.Nutrients · 2023Review
- A review of current evidence on food allergies during pregnancy.Food science & nutrition · 2023Review
- The SunBEAm birth cohort: Protocol design.The journal of allergy and clinical immunology. Global · 2023Article
- Sex Differences in Neurodevelopmental Disorders: A Key Role for the Immune System.Current topics in behavioral neurosciences · 2023Article
- Androgen receptor signaling protects male mice from the development of immune response to peanut.American journal of clinical and experimental immunology · 2023Article
- Immune Responses at Host Barriers and Their Importance in Systemic Autoimmune Diseases.Advances in experimental medicine and biology · 2023Review
- Changes in risk factors for food sensitization in early life: Analysis over a period of 10 years.Frontiers in immunology · 2023Article
- Sex Differences in Mast Cell-Associated Disorders: A Life Span Perspective.Cold Spring Harbor perspectives in biology · 2022Review
- Biological sex: an understudied factor driving disease susceptibility in pigs.Journal of animal science · 2022Review
- Burden of allergic disease among ethnic minority groups in high-income countries.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2022Review
- Clinical notes: An untapped opportunity for improving risk prediction for hospitalization and emergency department visit during home health care.Journal of biomedical informatics · 2022Article
- Exploring prevalence of wound infections and related patient characteristics in homecare using natural language processing.International wound journal · 2022Article
Corrections and comments
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Authors and funding
10 authors at 6 institutions in 2 countries.
Funding
Abstract
backgroundFood allergy prevalence is reported to be increasing, but epidemiological data using patients' electronic health records (EHRs) remain sparse.
objectiveWe sought to determine the prevalence of food allergy and intolerance documented in the EHR allergy module.
methodsUsing allergy data from a large health care organization's EHR between 2000 and 2013, we determined the prevalence of food allergy and intolerance by sex, racial/ethnic group, and allergen group. We examined the prevalence of reactions that were potentially IgE-mediated and anaphylactic. Data were validated using radioallergosorbent test and ImmunoCAP results, when available, for patients with reported peanut allergy.
resultsAmong 2.7 million patients, we identified 97,482 patients (3.6%) with 1 or more food allergies or intolerances (mean, 1.4 ± 0.1). The prevalence of food allergy and intolerance was higher in females (4.2% vs 2.9%; P < .001) and Asians (4.3% vs 3.6%; P < .001). The most common food allergen groups were shellfish (0.9%), fruit or vegetable (0.7%), dairy (0.5%), and peanut (0.5%). Of the 103,659 identified reactions to foods, 48.1% were potentially IgE-mediated (affecting 50.8% of food allergy or intolerance patients) and 15.9% were anaphylactic. About 20% of patients with reported peanut allergy had a radioallergosorbent test/ImmunoCAP performed, of which 57.3% had an IgE level of grade 3 or higher.
conclusionsOur findings are consistent with previously validated methods for studying food allergy, suggesting that the EHR's allergy module has the potential to be used for clinical and epidemiological research. The spectrum of severity observed with food allergy highlights the critical need for more allergy evaluations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.