Evidence map›Paper›PMID 28577925›Full record

ReviewSeminars in cell & developmental biology2017

Molecular and cytoskeletal regulations in epidermal development.

Jimmy Lee, Philbert Lee, Xiaoyang Wu

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in cell & developmental biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Keratinocytes: A key player in skin immunity and their emerging roles in secondary lymphedema.JID innovations : skin science from molecules to population health · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Pharmaceuticals (Basel, Switzerland) · 2022
    Article
  10. Review
  11. Keratinocytes: innate immune cells in atopic dermatitis.Clinical and experimental immunology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jimmy LeeBen May Department for Cancer Research, University of Chicago, Chicago, IL, USA.
Philbert LeeBen May Department for Cancer Research, University of Chicago, Chicago, IL, USA.
Xiaoyang WuBen May Department for Cancer Research, University of Chicago, Chicago, IL, USA. Electronic address: xiaoyangwu@uchicago.edu.
University of Chicago · US

Funding

Development of epidermal progenitor cell-based therapy for regenerative medicineR01OD023700 · OD · UNIVERSITY OF CHICAGO · PI WU, XIAOYANG · 2017 to 2021
$2.4M
Coordinated cytoskeletal dynamics in skin somatic stem cells - Resubmission 01R01AR063630 · NIAMS · UNIVERSITY OF CHICAGO · PI WU, XIAOYANG · 2013 to 2017
$1.7M
NIAMS NIH HHS R01 AR063630NIH HHS R01 OD023700
6 · The paper itself

Abstract

At the surface of the body, the epidermis covers great depth in its developmental regulation. While many genes have been shown to be important for skin development through their associations with disease phenotypes in mice and human, it is in the past decade that the intricate interplay between various molecules become gradually revealed through sophisticated genetic models and imaging analyses. In particular, there is increasing evidence suggesting that cytoskeleton-associated proteins, including adhesion proteins and the crosslinker proteins may play critical roles in regulating epidermis development. We here provide a broad overview of the various molecules involved in epidermal development with special emphasis on the cytoskeletal components.

Indexed as

AnimalsCell Adhesion MoleculesCytoskeletonEpidermisHumansMicrofilament ProteinsCell Adhesion MoleculesMicrofilament ProteinsCell junctionCytoskeletonMolecular mechanismSkin developmentSpectraplakin

Identifiers

PMID28577925
PMCPMC5583032
OpenAlexW2620758899

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.