Evidence map›Paper›PMID 28577766›Full record

ReviewGastrointestinal endoscopy clinics of North America2017

Beyond Dysplasia Grade: The Role of Biomarkers in Stratifying Risk.

Kerry B Dunbar, Rhonda F Souza

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Gastrointestinal endoscopy clinics of North America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Kerry B DunbarDivision of Gastroenterology and Hepatology, Department of Medicine, Esophageal Diseases Center, Dallas VA Medical Center, VA North Texas Health Care System, University of Texas Southwestern Medical Center, CA 111-B1, 4500 South Lancaster Road, Dallas, TX 75216, USA.
Rhonda F SouzaCenter for Esophageal Diseases, Department of Medicine, Baylor University Medical Center and Center for Esophageal Research, Baylor Scott and White Research Institute, 2 Hoblitzelle, Suite 250, 3500 Gaston Avenue, Dallas, TX 75246, USA.
Baylor Medical Center at Garland · USThe University of Texas Southwestern Medical Center · US

Funding

Role of Acid in the Development of Barrett's EsophagusR01DK063621 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI SOUZA, RHONDA F, SPECHLER, STUART JON · 2002 to 2015
$3.4M
Reflux-Induced Epithelial-Mesenchymal Transition in Benign Barrett's EsophagusR01DK103598 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI SOUZA, RHONDA F, SPECHLER, STUART JON · 2015 to 2019
$1.7M
NIDDK NIH HHS R01 DK063621NIDDK NIH HHS R01 DK103598
6 · The paper itself

Abstract

Gastroenterology society guidelines recommend endoscopic surveillance as a means to detect early stage cancer in Barrett's esophagus. However, the incidence of esophageal adenocarcinoma in Western countries continues to increase, suggesting that this strategy may be inadequate. Current surveillance methods rely on the endoscopist's ability to identify suspicious areas of Barrett's esophagus to biopsy, random biopsies, and on the histopathologic diagnosis of dysplasia. This review highlights the challenges of using dysplasia to stratify cancer risk and addresses the development and use of molecular biomarkers and in vivo molecular imaging to detect early neoplasia in Barrett's esophagus.

Indexed as

BiomarkersAdenocarcinomaBarrett EsophagusBiopsyEsophageal NeoplasmsEsophagoscopyHumansRiskRisk AssessmentBiomarkersBarrett’s esophagusBiomarkerConfocal laser endomicroscopyDysplasiaFluorescence endoscopyIn vivo imaging

Identifiers

PMID28577766
PMCPMC5458534
OpenAlexW2621053453

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.