ReviewDental clinics of North America2017
Precision Dentistry in Early Childhood: The Central Role of Genomics.
Review in Dental clinics of North America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Prognostic Clinical Predictive Models for Dental Caries Using Artificial Intelligence: Methodological Considerations.Caries research · 2026Review
- Development of a Secondary Dental-Specific Database for Active Learning of Genetics in Dentistry Programs.Healthcare informatics research · 2022Article
- Replication of GWAS significant loci in a sub-Saharan African Cohort with early childhood caries: a pilot study.BMC oral health · 2021Article
- Overexpression of miR-1306-5p, miR-3195, and miR-3914 Inhibits Ameloblast Differentiation through Suppression of Genes Associated with Human Amelogenesis Imperfecta.International journal of molecular sciences · 2021Article
- Examining Parental Treatment Decisions Within a Contemporary Pediatric Dentistry Private Practice.Patient preference and adherence · 2021Article
- Cohort Profile: ZOE 2.0-A Community-Based Genetic Epidemiologic Study of Early Childhood Oral Health.International journal of environmental research and public health · 2020Article
- The building blocks of precision oral health in early childhood: the ZOE 2.0 study.Journal of public health dentistry · 2020Article
- Genomics of periodontal disease and tooth morbidity.Periodontology 2000 · 2020Review
- Searching Deep and Wide: Advances in the Molecular Understanding of Dental Caries and Periodontal Disease.Advances in dental research · 2019Article
- Human genes influence the interaction between Streptococcus mutans and host caries susceptibility: a genome-wide association study in children with primary dentition.International journal of oral science · 2019Article
- Measurement of Early Childhood Oral Health for Research Purposes: Dental Caries Experience and Developmental Defects of the Enamel in the Primary Dentition.Methods in molecular biology (Clifton, N.J.) · 2019Article
- The Supragingival Biofilm in Early Childhood Caries: Clinical and Laboratory Protocols and Bioinformatics Pipelines Supporting Metagenomics, Metatranscriptomics, and Metabolomics Studies of the Oral Microbiome.Methods in molecular biology (Clifton, N.J.) · 2019Article
- Exploring the genomic basis of early childhood caries: a pilot study.International journal of paediatric dentistry · 2018Article
- Fundamentals of Precision Medicine.Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995) · 2017Article
- A Contemporary Examination of First and Second Permanent Molar Emergence.Journal of dental research · 2017Article
- Precision periodontology through periodontal endophenotyping: A narrative review.Journal of Indian Society of PeriodontologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Pediatric oral health is determined by the interaction of environmental factors and genetic influences. This is the case for early childhood caries, the most common disease of childhood. The complexity of exogenous-environmental factors interacting with innate biological predispositions results in a continuum of normal variation, as well as oral health and disease outcomes. Optimal oral health and care or precision dentistry warrants comprehensive understanding of these influences and tools enabling intervention on modifiable factors. This article reviews the current knowledge of the genomic basis of pediatric oral health and highlights known and postulated mechanistic pathways of action relevant to early childhood caries.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.