Evidence map›Paper›PMID 28577268›Full record

ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2017

The predictive accuracy of the black hole sign and the spot sign for hematoma expansion in patients with spontaneous intracerebral hemorrhage.

Zhiyuan Yu, Jun Zheng, Lu Ma, Rui Guo, Mou Li, Xiaoze Wang, Sen Lin, Hao Li, Chao You

Abstract read
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In one paragraph

Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhiyuan YuDepartment of Neurosurgery, West China Hospital, Sichuan University, Xiang Street, Chengdu, Sichuan, 610041, People's Republic of China.
Jun ZhengDepartment of Neurosurgery, West China Hospital, Sichuan University, Xiang Street, Chengdu, Sichuan, 610041, People's Republic of China.
Lu MaDepartment of Neurosurgery, West China Hospital, Sichuan University, Xiang Street, Chengdu, Sichuan, 610041, People's Republic of China.
Rui GuoDepartment of Neurosurgery, West China Hospital, Sichuan University, Xiang Street, Chengdu, Sichuan, 610041, People's Republic of China.
Mou LiDepartment of Radiology, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China.
Xiaoze WangDepartment of Radiology, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China.
Sen LinDepartment of Neurosurgery, West China Hospital, Sichuan University, Xiang Street, Chengdu, Sichuan, 610041, People's Republic of China.
Hao LiDepartment of Neurosurgery, West China Hospital, Sichuan University, Xiang Street, Chengdu, Sichuan, 610041, People's Republic of China.
Chao YouDepartment of Neurosurgery, West China Hospital, Sichuan University, Xiang Street, Chengdu, Sichuan, 610041, People's Republic of China. youchaowchscu@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In patients with spontaneous intracerebral hemorrhage (sICH), hematoma expansion (HE) is associated with poor outcome. Spot sign and black hole sign are neuroimaging predictors for HE. This study was aimed to compare the predictive value of two signs for HE. Within 6 h after onset of sICH, patients were screened for the computed tomography angiography spot sign and the non-contrast computed tomography black hole sign. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of two signs for HE prediction were calculated. The accuracy of two signs in predicting HE was analyzed by receiver-operator analysis. A total of 129 patients were included in this study. Spot sign was identified in 30 (23.3%) patients and black hole sign in 29 (22.5%) patients, respectively. Of 32 patients with HE, spot sign was observed in 19 (59.4%) and black hole sign was found in 14 (43.8%). The occurrence of black hole sign was significantly associated with spot sign (P < 0.001). The sensitivity, specificity, PPV, and NPV of spot sign for predicting HE were 59.38, 88.66, 63.33, and 86.87% respectively. In contrast, the sensitivity, specificity, PPV, and NPV of black hole sign for predicting HE were 43.75, 84.54, 48.28, and 82.00%, respectively. The area under the curve was 0.740 for spot sign and 0.641 for black hole sign. (P = 0.228) Both spot sign and black hole sign appeared to have good predictive value for HE, and spot sign seemed to be a better predictor.

Indexed as

Cerebral AngiographyTomography, X-Ray ComputedAdultAgedAged, 80 and overBrainCerebral HemorrhageDisease ProgressionFemaleFollow-Up StudiesHematomaHumansMaleMiddle AgedMultivariate AnalysisPrognosisBlack hole signHematoma expansionSpontaneous intracerebral hemorrhageSpot sign

Identifiers

PMID28577268

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.