ReviewMycopathologia2017
Hepatic Disease with Portal Hypertension and Acute Juvenile Paracoccidioidomycosis: A Report of Two Cases and Literature Review.
Review in Mycopathologia, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 11 citations in OpenAlex.
- Disseminated juvenile paracoccidioidomycosis: a case report and literature review.Einstein (Sao Paulo, Brazil) · 2026Review
- Chylothorax and chylous ascites due to juvenile paracoccidioidomycosis: a case report.Revista da Sociedade Brasileira de Medicina Tropical · 2023Article
- Updates inJournal of fungi (Basel, Switzerland) · 2021Review
- Clinical features and genetic background of the sympatric species Paracoccidioides brasiliensis and Paracoccidioides americana.PLoS neglected tropical diseases · 2019Article
- Promising New Antifungal Treatment Targeting Chorismate Synthase fromAntimicrobial agents and chemotherapy · 2019Article
- Paracoccidioidomycosis due to Paracoccidioides brasiliensis S1 plus HIV co-infection.Memorias do Instituto Oswaldo Cruz · 2018Article
- Severe paracoccidioidomycosis, with a fatal outcome and incidence related to an environmental event.Anais brasileiros de dermatologiaArticle
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
Paracoccidioidomycosis (PCM) is a neglected systemic mycosis endemic to Latin America caused by dimorphic fungi of the genus Paracoccidioides. The acute juvenile PCM is a severe type of presentation that usually affects young vulnerable patients and rarely progresses to portal hypertension. Here, two cases of liver disease and portal hypertension as complications of acute juvenile PCM are reported. Diagnosis of PCM was performed by isolation of the fungus and molecular identification of the strains provided through partial sequencing of two protein encoding genes, arf and gp43. Genotypic analysis revealed that Paracoccidioides brasiliensis S1 was the phylogenic species involved in both cases. Patients presented a good clinical response to amphotericin B and sulfamethoxazole-trimethoprim. These results highlight the importance of the interdisciplinary approach in patients with severe forms of PCM to avoid and treat complications, and the necessity of further investigations focusing on host-pathogen interaction in order to explain the broad clinical spectrum in PCM as well as the severity and poor outcome in some clinical cases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.