Evidence map›Paper›PMID 28577119›Full record

ArticleMammalian genome : official journal of the International Mammalian Genome Society2017

Gene networks for total number born in pigs across divergent environments.

Lucas L Verardo, Marcos S Lopes, Pramod Mathur, Ole Madsen, Fabyano F Silva, Martien A M Groenen, Egbert F Knol, Paulo S Lopes, Simone E F Guimarães

Abstract read
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In one paragraph

Article in Mammalian genome : official journal of the International Mammalian Genome Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Association ofAnimals : an open access journal from MDPI · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lucas L VerardoDepartment of Animal Science, Universidade Federal de Viçosa, Viçosa, MG, 36570000, Brazil. lucas.verardo@ufv.br.
Marcos S LopesTopigs Norsvin Research Center, 6641 SZ, Beuningen, The Netherlands.
Pramod MathurTopigs Norsvin Research Center, 6641 SZ, Beuningen, The Netherlands.
Ole MadsenAnimal Breeding and Genomics Centre, Wageningen University, 6700 AH, Wageningen, The Netherlands.
Fabyano F SilvaDepartment of Animal Science, Universidade Federal de Viçosa, Viçosa, MG, 36570000, Brazil.
Martien A M GroenenAnimal Breeding and Genomics Centre, Wageningen University, 6700 AH, Wageningen, The Netherlands.
Egbert F KnolTopigs Norsvin Research Center, 6641 SZ, Beuningen, The Netherlands.
Paulo S LopesDepartment of Animal Science, Universidade Federal de Viçosa, Viçosa, MG, 36570000, Brazil.
Simone E F GuimarãesDepartment of Animal Science, Universidade Federal de Viçosa, Viçosa, MG, 36570000, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For reproductive traits such as total number born (TNB), variance due to different environments is highly relevant in animal breeding. In this study, we aimed to perform a gene-network analysis for TNB in pigs across different environments using genomic reaction norm models. Thus, based on relevant single-nucleotide polymorphisms and linkage disequilibrium blocks across environments obtained from GWAS, different sets of candidate genes having biological roles linked to TNB were identified. Network analysis across environment levels resulted in gene interactions consistent with known mammal's fertility biology, captured relevant transcription factors for TNB biology and pointing out different sets of candidate genes for TNB in different environments. These findings may have important implication for animal production, as optimal breeding may vary depending on later environments. Based on these results, genomic diversity was identified and inferred across environments highlighting differential genetic control in each scenario.

Indexed as

EnvironmentGene Regulatory NetworksAnimalsBreedingGenotypeLinkage DisequilibriumLitter SizeMaleModels, GeneticPhenotypePolymorphism, Single NucleotideSequence Analysis, DNASus scrofaTranscription FactorsTranscription Factors

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.