Evidence map›Paper›PMID 28576978›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2017

Catherine Ptaschinski, Steven M Hrycaj, Matthew A Schaller, Deneen M Wellik, Nicholas W Lukacs

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. The Lung Elastin Matrix Undergoes Rapid Degradation Upon Adult Loss ofFrontiers in cell and developmental biology · 2021
    Article
  8. Article
  9. Review
  10. Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Catherine PtaschinskiDepartment of Pathology, University of Michigan, Ann Arbor, MI 48109; and cptaschi@umich.edu.
Steven M HrycajDivision of Molecular Medicine and Genetics, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109.
Matthew A SchallerDepartment of Pathology, University of Michigan, Ann Arbor, MI 48109; and.ORCID 0000-0003-3338-0655
Deneen M WellikDivision of Molecular Medicine and Genetics, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109.ORCID 0000-0003-4078-8560
Nicholas W LukacsDepartment of Pathology, University of Michigan, Ann Arbor, MI 48109; and.ORCID 0000-0003-2403-6481
University of Michigan · US

Funding

Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Mehboob A Hussain · 2013 to 2026
$24.3M
The Role of C-C Chemokines in Eosinophil Airway InflammationR01AI036302 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUKACS, NICHOLAS W · 2001 to 2018
$5.6M
Supplement to a Hox-Wnt-Sox signaling axis regulates lung development, patterning and branchingR01HL119215 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SPENCE, JASON · 2013 to 2021
$4.2M
Hox5 gene regulation of lung fibrobroblasts and distal lung extracellular matrixR01HL144086 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI WELLIK, DENEEN M · 2018 to 2021
$1.8M
Antigen biased positive selection of CD4+ T cellsR01HD036302 · NICHD · MEDICAL COLLEGE OF GEORGIA (MCG) · PI IGNATOWICZ, LESZEK · 1997 to 2006
$1.4M
NHLBI NIH HHS R01 HL119215NHLBI NIH HHS R01 HL144086NIAID NIH HHS R01 AI036302NICHD NIH HHS R01 HD036302NIDDK NIH HHS P30 DK020572
6 · The paper itself

Abstract

Allergic asthma is a significant health burden in western countries, and continues to increase in prevalence. Th2 cells contribute to the development of disease through release of the cytokines IL-4, IL-5, and IL-13, resulting in increased airway eosinophils and mucus hypersecretion. The molecular mechanisms behind the disease pathology remain largely unknown. In this study we investigated a potential regulatory role for the

Indexed as

Gene Expression RegulationAllergensAnimalsCell ProliferationGATA3 Transcription FactorHedgehog ProteinsHomeodomain ProteinsHumansInflammationInterleukin-13Interleukin-4Interleukin-5Jurkat CellsLungMesodermMiceAllergensGata3 protein, mouseGATA3 Transcription FactorHedgehog ProteinsHomeodomain ProteinsHoxa5 protein, mouseHoxb5 protein, mouseInterleukin-13Interleukin-4Interleukin-5PhosphoproteinsTranscription Factors

Identifiers

PMID28576978
PMCPMC5508748
OpenAlexW2621109624

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.