Evidence map›Paper›PMID 28576943›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2017

Polysialic Acid Regulates Sympathetic Outflow by Facilitating Information Transfer within the Nucleus of the Solitary Tract.

Phillip Bokiniec, Shila Shahbazian, Stuart J McDougall, Britt A Berning, Delfine Cheng, Ida J Llewellyn-Smith, Peter G R Burke, Simon McMullan, Martina Mühlenhoff, Herbert Hildebrandt and 4 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Brain-wide connectivity map of mouse thermosensory cortices.Cerebral cortex (New York, N.Y. : 1991) · 2023
    Article
  2. A Student's Guide to Neural Circuit Tracing.Frontiers in neuroscience · 2019
    Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 2 countries.

Phillip BokiniecDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, 2109 New South Wales, Australia.ORCID 0000-0002-3139-4765
Shila ShahbazianDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, 2109 New South Wales, Australia.
Stuart J McDougallFlorey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, 3010 Victoria, Australia.ORCID 0000-0002-8778-675X
Britt A BerningDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, 2109 New South Wales, Australia.
Delfine ChengSchool of Medical Sciences, Discipline of Anatomy and Histology, University of Sydney, Sydney, 2006 New South Wales, Australia.ORCID 0000-0002-8575-0534
Ida J Llewellyn-SmithCardiovascular Medicine and Human Physiology, Flinders University, Adelaide, 5042 South Australia, Australia.ORCID 0000-0003-4269-6846
Peter G R BurkeNeuroscience Research Australia, Sydney, 2031 New South Wales, Australia.ORCID 0000-0002-6896-3298
Simon McMullanDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, 2109 New South Wales, Australia.ORCID 0000-0002-9854-1029
Martina MühlenhoffInstitut für Zelluläre Chemie, Medizinische Hochschule Hannover, Hannover 30625, Germany.ORCID 0000-0002-6070-8241
Herbert HildebrandtInstitut für Zelluläre Chemie, Medizinische Hochschule Hannover, Hannover 30625, Germany.ORCID 0000-0002-1044-0881
Filip BraetSchool of Medical Sciences, Discipline of Anatomy and Histology, University of Sydney, Sydney, 2006 New South Wales, Australia.
Mark ConnorDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, 2109 New South Wales, Australia.ORCID 0000-0003-2538-2001
Nicolle H PackerARC Centre of Excellence in Nanoscale Biophotonics, Macquarie University, Sydney, 2109 New South Wales, Australia, and.ORCID 0000-0002-7532-4021
Ann K GoodchildDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, 2109 New South Wales, Australia, ann.goodchild@mq.edu.au.ORCID 0000-0003-1544-7924
Macquarie University · AUMedizinische Hochschule Hannover · DEThe University of Sydney · AUFlinders University · AUMax Delbrück Center · DENeuroscience Research Australia · AUThe University of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Expression of the large extracellular glycan, polysialic acid (polySia), is restricted in the adult, to brain regions exhibiting high levels of plasticity or remodeling, including the hippocampus, prefrontal cortex, and the nucleus of the solitary tract (NTS). The NTS, located in the dorsal brainstem, receives constant viscerosensory afferent traffic as well as input from central regions controlling sympathetic nerve activity, respiration, gastrointestinal functions, hormonal release, and behavior. Our aims were to determine the ultrastructural location of polySia in the NTS and the functional effects of enzymatic removal of polySia, both

Indexed as

Afferent PathwaysAnimalsExcitatory Postsynaptic PotentialsMaleNerve NetNeuronal PlasticityRatsRats, Sprague-DawleySialic AcidsSolitary NucleusSympathetic Nervous SystemTissue Distributionpolysialic acidSialic Acidselectron microscopynucleus of the solitary tractpatch clamppolysialic acidsympathetic nerve activityviscerosensory afferents

Identifiers

PMID28576943
PMCPMC6596603
OpenAlexW2621095299

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.