Evidence map›Paper›PMID 28576891›Full record

ArticleBMJ open2017

The effect of life course socioeconomic position on crystallised cognitive ability in two large UK cohort studies: a structured modelling approach.

Rebecca Landy, Jenny Head, Marcus Richards, Rebecca Hardy

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Article in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The Power of Birth Cohorts to Study Risk Factors for Cognitive Impairment.Current neurology and neuroscience reports · 2022
    Review
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rebecca LandyCentre for Cancer Prevention, Wolfson Institute of Preventive Medicine, Barts and The London School of Medicine, Queen Mary University of London, London, UK.
Jenny HeadDepartment of Epidemiology and Public Health, University College London, London, UK.
Marcus RichardsMRC Unit for Lifelong Health and Ageing at UCL, University College London, London, UK.
Rebecca HardyMRC Unit for Lifelong Health and Ageing at UCL, University College London, London, UK.

Funding

Socio-economic status and heterogeneity in agingR01AG013196 · NIA · UNIVERSITY OF LONDON INST OF NEUROLOGY · PI MARMOT, MICHAEL G, SINGH-MANOUX, ARCHANA · 1996 to 2013
$3.5M
Socioeconomic gradient in CHD in early old ageR01HL036310 · NHLBI · UNIVERSITY OF LONDON · PI KIVIMAKI, MIKA J, MARMOT, MICHAEL G · 1986 to 2012
$3.1M
British Heart FoundationMedical Research Council MC_UU_12019/1Medical Research Council MC_UU_12019/2Medical Research Council MC_UU_12019/3NHLBI NIH HHS R01 HL036310NIA NIH HHS R01 AG013196
6 · The paper itself

Abstract

objectivesThis study systematically compared accumulation, sensitive period, critical period and social mobility models relating life course socioeconomic position (SEP) and adult crystallised cognitive ability, which has not been comprehensively investigated.

designTwo prospective cohort studies.

participantsFive thousand three hundred and sixty-two participants in the Medical Research Council National Survey of Health and Development (NSHD) Birth Cohort Study and 10 308 participants in the Whitehall II Occupational Cohort Study. MEASURES: Childhood SEP was measured by father's occupational SEP, early adulthood SEP by educational qualifications and adult SEP by own occupational SEP. Each life course model was compared with a saturated model.

resultsUsing multiple imputation to account for missing data, the sensitive period model, which contained childhood, early adulthood and adult SEP terms, with different coefficients, provided the best fit for both men and women in the NSHD and Whitehall II cohorts. Early adulthood SEP had the largest coefficient in NSHD women, whereas for NSHD men early adulthood and adult SEP had similar coefficients. In Whitehall II adult SEP had the largest effect size for both men and women.

conclusionsSensitive period with all three time periods was the most appropriate life course models for adult crystallised cognitive ability in both cohorts, including an effect of childhood SEP. It is important to directly compare the life course models to determine which is the most appropriate.

Indexed as

CognitionIntelligenceSocial ClassAdultAgedAge FactorsFemaleHumansMaleMiddle AgedModels, StructuralProspective StudiesUnited Kingdomcioeconomic positioncognitive functioncohort studieslife course

Identifiers

PMID28576891
PMCPMC5541359

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.