Evidence map›Paper›PMID 28576872›Full record

ArticleThe Journal of endocrinology2017

Origin of a rapidly evolving homeostatic control system programming testis function.

Pengli Bu, Shintaro Yagi, Kunio Shiota, S M Khorshed Alam, Jay L Vivian, Michael W Wolfe, M A Karim Rumi, Damayanti Chakraborty, Kaiyu Kubota, Pramod Dhakal and 1 more

Abstract read
In one paragraph

Article in The Journal of endocrinology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Pengli BuInstitute for Reproductive Health and Regenerative MedicineUniversity of Kansas Medical Center, Kansas City, Kansas, USA.
Shintaro YagiLaboratory of Cellular BiochemistryVeterinary Medical Sciences/Animal Resource Sciences, The University of Tokyo, Tokyo, Japan.
Kunio ShiotaLaboratory of Cellular BiochemistryVeterinary Medical Sciences/Animal Resource Sciences, The University of Tokyo, Tokyo, Japan.
S M Khorshed AlamInstitute for Reproductive Health and Regenerative MedicineUniversity of Kansas Medical Center, Kansas City, Kansas, USA.
Jay L VivianInstitute for Reproductive Health and Regenerative MedicineUniversity of Kansas Medical Center, Kansas City, Kansas, USA.
Michael W WolfeInstitute for Reproductive Health and Regenerative MedicineUniversity of Kansas Medical Center, Kansas City, Kansas, USA.
M A Karim RumiInstitute for Reproductive Health and Regenerative MedicineUniversity of Kansas Medical Center, Kansas City, Kansas, USA.
Damayanti ChakrabortyInstitute for Reproductive Health and Regenerative MedicineUniversity of Kansas Medical Center, Kansas City, Kansas, USA.
Kaiyu KubotaInstitute for Reproductive Health and Regenerative MedicineUniversity of Kansas Medical Center, Kansas City, Kansas, USA.
Pramod DhakalInstitute for Reproductive Health and Regenerative MedicineUniversity of Kansas Medical Center, Kansas City, Kansas, USA.
Michael J SoaresInstitute for Reproductive Health and Regenerative MedicineUniversity of Kansas Medical Center, Kansas City, Kansas, USA msoares@kumc.edu.

Funding

PROJECT 3 - Steroid-Metabolic Interactions In the Control of GnRH NeuronsU54HD028934 · NICHD · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI MARSHALL, JOHN C · 1998 to 2013
$16.5M
TROPHOBLAST DIFFERENTIATIONR01HD020676 · NICHD · UNIVERSITY OF KANSAS MEDICAL CENTER · PI MICHAEL J SOARES · 1986 to 2026
$10.1M
TRAINING PROGRAM IN ENVIRONMENTAL TOXICOLOGYT32ES007079 · NIEHS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI HAGENBUCH, BRUNO · 1985 to 2015
$4.1M
Decidual Cell Adaptations to Physiological StressorsR01HD055523 · NICHD · UNIVERSITY OF KANSAS MEDICAL CENTER · PI SOARES, MICHAEL J · 2007 to 2011
$1.5M
Genetics of DecidualizationR21HD060115 · NICHD · UNIVERSITY OF KANSAS MEDICAL CENTER · PI SOARES, MICHAEL J · 2010 to 2011
$404k
NICHD NIH HHS R01 HD020676NICHD NIH HHS R01 HD055523NICHD NIH HHS R21 HD060115NICHD NIH HHS U54 HD028934NIEHS NIH HHS T32 ES007079
6 · The paper itself

Abstract

Mammals share common strategies for regulating reproduction, including a conserved hypothalamic-pituitary-gonadal axis; yet, individual species exhibit differences in reproductive performance. In this report, we describe the discovery of a species-restricted homeostatic control system programming testis growth and function.

Indexed as

AnimalsFemaleGene Expression RegulationGlycoproteinsHomeostasisIntercellular Signaling Peptides and ProteinsMaleMiceMice, Inbred StrainsMice, KnockoutMultigene FamilyProlactinProtein IsoformsRatsTestisGlycoproteinsIntercellular Signaling Peptides and ProteinsPrlpi protein, mouseProlactinProtein IsoformsLeydig cellsprolactin familytestistransposable elements

Identifiers

PMID28576872
PMCPMC5529123

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.