Evidence map›Paper›PMID 28576866›Full record

ArticleGenetics2017

Heat-Induced Calcium Leakage Causes Mitochondrial Damage in

Kenta Momma, Takashi Homma, Ruri Isaka, Surabhi Sudevan, Atsushi Higashitani

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. The RyR-like-FKBP12-PKA Complex Regulates Intracellular CaInternational journal of molecular sciences · 2026
    Article
  3. Article
  4. Functional Analysis of Late-Onset Alzheimer's Disease Risk Genes inbioRxiv : the preprint server for biology · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Biological sex impacts oxidative stress in skeletal muscle in a porcine heat stress model.American journal of physiology. Regulatory, integrative and comparative physiology · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Frontiers in nutrition · 2022
    Article
  18. Article
  19. Drp-1-Dependent Mitochondrial Fragmentation Contributes to Cobalt Chloride-Induced Toxicity in Caenorhabditis elegans.Toxicological sciences : an official journal of the Society of Toxicology · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kenta MommaGraduate School of Life Sciences, Tohoku University, Sendai 980-8577, Japan.
Takashi HommaGraduate School of Life Sciences, Tohoku University, Sendai 980-8577, Japan.
Ruri IsakaGraduate School of Life Sciences, Tohoku University, Sendai 980-8577, Japan.
Surabhi SudevanGraduate School of Life Sciences, Tohoku University, Sendai 980-8577, Japan.
Atsushi HigashitaniGraduate School of Life Sciences, Tohoku University, Sendai 980-8577, Japan ahigashi@m.tohoku.ac.jp.ORCID 0000-0001-6920-0594
Tohoku University · JP

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
NIH HHS P40 OD010440
6 · The paper itself

Abstract

Acute onset of organ failure in heatstroke is triggered by rhabdomyolysis of skeletal muscle. Here, we showed that elevated temperature increases free cytosolic Ca

Indexed as

Calcium SignalingHeat-Shock ResponseAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsCalciumDantroleneForkhead Transcription FactorsIonomycinMitochondria, MuscleMyofibrilsReceptor, InsulinRyanodine Receptor Calcium Release ChannelCaenorhabditis elegans ProteinsCalciumdaf-16 protein, C elegansDAF-2 protein, C elegansDantroleneForkhead Transcription FactorsIonomycinReceptor, InsulinRyanodine Receptor Calcium Release ChannelUnc-68 protein, C eleganscalciumDAF-16heat stressmitochondrial fragmentationryanodine receptor

Identifiers

PMID28576866
PMCPMC5560802
OpenAlexW2620870153

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.