Evidence map›Paper›PMID 28576864›Full record

ArticleGenetics2017

LIN-41 and OMA Ribonucleoprotein Complexes Mediate a Translational Repression-to-Activation Switch Controlling Oocyte Meiotic Maturation and the Oocyte-to-Embryo Transition in

Tatsuya Tsukamoto, Micah D Gearhart, Caroline A Spike, Gabriela Huelgas-Morales, Makaela Mews, Peter R Boag, Traude H Beilharz, David Greenstein

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 72 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Landscape and regulation of mRNA translation in the earlybioRxiv : the preprint server for biology · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Tatsuya TsukamotoDepartment of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota 55455.ORCID 0000-0001-5306-3791
Micah D GearhartDepartment of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota 55455.ORCID 0000-0002-9873-1930
Caroline A SpikeDepartment of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota 55455.
Gabriela Huelgas-MoralesDepartment of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota 55455.
Makaela MewsDepartment of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota 55455.
Peter R BoagDepartment of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria 3800, Australia.
Traude H BeilharzDepartment of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria 3800, Australia.ORCID 0000-0002-8942-9502
David GreensteinDepartment of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota 55455 green959@umn.edu.ORCID 0000-0001-8189-2087
University of Minnesota · USMonash University · AU

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
CONTROL OF MEIOSIS AND GERMLINE PROLIFERATIONR01GM057173 · NIGMS · VANDERBILT UNIVERSITY · PI GREENSTEIN, DAVID IRWIN · 1998 to 2021
$6.6M
Control of Meiosis and Germline ProliferationR56GM057173 · NIGMS · UNIVERSITY OF MINNESOTA · PI GREENSTEIN, DAVID IRWIN · 2008 to 2008
$310k
NIGMS NIH HHS R01 GM057173NIGMS NIH HHS R56 GM057173NIH HHS P40 OD010440
6 · The paper itself

Abstract

An extended meiotic prophase is a hallmark of oogenesis. Hormonal signaling activates the CDK1/cyclin B kinase to promote oocyte meiotic maturation, which involves nuclear and cytoplasmic events. Nuclear maturation encompasses nuclear envelope breakdown, meiotic spindle assembly, and chromosome segregation. Cytoplasmic maturation involves major changes in oocyte protein translation and cytoplasmic organelles and is poorly understood. In the nematode

Indexed as

MeiosisAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsCarrier ProteinsCell Cycle ProteinsHelminth ProteinsOocytesPolynucleotide AdenylyltransferaseRNA-Binding ProteinsSignal TransductionTranscription FactorsCaenorhabditis elegans ProteinsCarrier ProteinsCell Cycle ProteinsGLD-2 protein, C elegansHelminth ProteinsLIN-41 protein, C elegansmajor sperm protein, nematodeMEG-1 protein, C elegansOMA-1 protein, C elegansoma-2 protein, C elegansPolynucleotide AdenylyltransferaseRNA-Binding ProteinsSPN-4 protein, C elegansTranscription Factorscytoplasmic polyadenylationoocyte meiotic maturationribonucleoprotein particle purificationRNA-binding proteinstranslational regulation

Identifiers

PMID28576864
PMCPMC5560804
OpenAlexW2621049549

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.