Evidence map›Paper›PMID 28576857›Full record

ReviewThe oncologist2017

Emilie M J van Brummelen, Anthonius de Boer, Jos H Beijnen, Jan H M Schellens

Open access · bronzeAbstract readReview
In one paragraph

Review in The oncologist, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Response to Anti-EGFR Therapy in Patients with BRAF non-V600-Mutant Metastatic Colorectal Cancer.Clinical cancer research : an official journal of the American Association for Cancer Research · 2019
    Trial
  4. Trial
  5. Review
  6. MiR-31 as a predictive biomarker of cetuximab efficacy in metastatic colorectal cancer patients: systematic review.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. Article
  17. Identification ofOncology letters · 2021
    Article
  18. Article
  19. Article
  20. Cancers · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Emilie M J van BrummelenDepartment of Clinical Pharmacology, Amsterdam, The Netherlands.
Anthonius de BoerDivision of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.
Jos H BeijnenPharmacy The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Jan H M SchellensDepartment of Clinical Pharmacology, Amsterdam, The Netherlands j.schellens@nki.nl.
Utrecht University · NLUniversity of Amsterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, the American Society of Clinical Oncology (ASCO) and the European Society for Medical Oncology (ESMO) recommended that patients with epidermal growth factor receptor (EGFR)-expressing metastatic colorectal cancer could be treated with anti-EGFR monoclonal antibodies (mAbs) cetuximab and panitumumab only in absence of Rat-Sarcoma ( IMPLICATIONS FOR PRACTICE: In metastatic colorectal cancer (mCRC), therapy with anti-epidermal growth factor receptor (EGFR) monoclonal antibodies cetuximab and panitumumab is indicated in absence of

Indexed as

MutationAntibodies, MonoclonalAntineoplastic AgentsBiomarkers, TumorCetuximabColorectal NeoplasmsErbB ReceptorsHumansPanitumumabProto-Oncogene Proteins B-rafras ProteinsTreatment OutcomeAntibodies, MonoclonalAntineoplastic AgentsBiomarkers, TumorBRAF protein, humanCetuximabEGFR protein, humanErbB ReceptorsPanitumumabProto-Oncogene Proteins B-rafras ProteinsAnti‐epidermal growth factor receptorBRAFCetuximabPanitumumabPredictive biomarkerRAS

Identifiers

PMID28576857
PMCPMC5507642
OpenAlexW2621165134

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.